A critical review on therapeutic approaches of CRISPR-Cas9 in diabetes mellitus.

Diabetes mellitus (D.M.) is a common metabolic disorder caused mainly by combining two primary factors, which are (1) defects in insulin production by the pancreatic β-cells and (2) responsiveness of insulin-sensitive tissues towards insulin.

Posterity of nanoscience as lipid nanosystems for Alzheimer's disease regression.

Alzheimer's disease (AD) is a type of dementia that affects a vast number of people around the world, causing a great deal of misery and death. Evidence reveals a relationship between the presence of soluble Aβ peptide aggregates and the severity of dementia in Alzheimer's patients. The BBB (Blood Brain Barrier) is a key problem in Alzheimer's disease because it prevents therapeutics from reaching the desired places.

Ebola Virus Disease Vaccines: Development, Current Perspectives & Challenges.

The global outgoing outbreaks of Ebola virus disease (EVD) in different regions of Sudan, Uganda, and Western Africa have brought into focus the inadequacies and restrictions of pre-designed vaccines for use in the battle against EVD, which has affirmed the urgent need for the development of a systematic protocol to produce Ebola vaccines prior to an outbreak. There are several vaccines available being developed by preclinical trials and human-based clinical trials. The group of vaccines includes virus-like particle-based vaccines, DNA-based vaccines, whole virus recombinant vaccines, incompetent replication originated vaccines, and competent replication vaccines.

Artificial Intelligence in Biological Sciences.

Artificial intelligence (AI), currently a cutting-edge concept, has the potential to improve the quality of life of human beings. The fields of AI and biological research are becoming more intertwined, and methods for extracting and applying the information stored in live organisms are constantly being refined. As the field of AI matures with more trained algorithms, the potential of its application in epidemiology, the study of host-pathogen interactions and drug designing widens.

A comprehensive review on removal of pollutants from wastewater through microbial nanobiotechnology -based solutions.

Increasing wastewater pollution owing to the briskly rising human population, rapid industrialization, and fast urbanization has necessitated highly efficient wastewater treatment technologies. Although several methods of wastewater treatments are in practice, expensiveness, use of noxious chemicals, generation of unsafe by-products, and longer time consumption restrain their use to a great extent. Over the last few decades, nanotechnological wastewater treatment approaches have received widespread recognition globally.

A comprehensive review on emerging trends in industrial wastewater research.

Rapid industrialization is one of the intricate factors that is linked to the depletion of water resources and increased generation of wastewater. Due to various obstructions and impediments, such as ineffective treatment solutions, exorbitant prices, lack of basic amenities, insufficient financial assistance, and technical expertise, sustainable treatment of industrial effluents has become an onerous process in most parts of the world. The majority of current treatment solutions are conventional and outdated, and thus fall short to remove all the contaminants efficiently from the industrial wastewater.

A comprehensive review on nanobiotechnology for bioremediation of heavy metals from wastewater.

Removal of contaminants from wastewater is a big concern for the scientific community. Heavy metals are one of the major contaminants present in wastewater. Heavy metals such as Cd , Pb , Mn , and so forth, are highly toxic and pose a serious threat to the environment due to their nonbiodegradable nature.

A perspective review on impact and molecular mechanism of environmental carcinogens on human health.

Cancer is one of the leading causes of death all around the world. It is a group of diseases characterized by abnormal and uncontrollable division of cells leading to severe health conditions and fatality if remains undiagnosed till later stages. Cancer can be caused due to mutation or sudden alterations by effect of certain external agents.