Publications by authors named "Shrikrishna Rajagopala"
Article Synopsis
- - Breast cancer is the leading cause of cancer-related deaths among women globally, with ongoing issues like drug resistance and metastasis despite treatment advancements.
- - The study investigates the potential of five natural compounds in a herbal formulation called Krishnadi Churna to target specific genes involved in breast cancer, using network pharmacology to identify and assess these interactions.
- - Key genes linked to breast cancer progression were found to be frequently mutated in patients, and the herbal compounds showed promising binding affinity, indicating their potential as new treatment options for breast cancer.
Context: SARS-CoV-2 is a global public-health concern. Interventions to prevent infection are urgently needed. The anti-inflammatory and antiviral effects of neem make it a potential agent for COVID-19 prophylaxis.
View Article and Find Full Text PDFThe present single-centered randomized control trial (RCT) was carried out with the prime aim of assessing the effect of Kasahara Dashemani Vati (trial drug) on Kasa and Vyadhikshamatva in the children suffering from recurrent respiratory tract infections and comparing it with the efficacy of Indukanta Vati. The clinical trial included 40 patients belonging to age group of 3-12 years. The drugs were administered in a daily dose fixed as per "Clark's Rule" along with honey for duration of 60 days.
View Article and Find Full Text PDFCommunity level morbidity control of lymphoedema using self care and integrative treatment in two lymphatic filariasis endemic districts of South India: a non randomized interventional study.
Trans R Soc Trop Med Hyg
September 2013
Background: Currently there is no global program to manage lymphoedema as a result of lymphatic filariasis (LF). The primary aim of this study was to determine the efficacy of a previously proposed integrative treatment protocol, using locally available resources to address the morbidity, in a community village setting.
Methods: Two LF endemic districts of south India, Gulbarga in Karnataka (GK) and Alleppey in Kerala (AK), were selected for the study.