Basic Science and Pathogenesis.

Background: Identification of cell-type vulnerability in Alzheimer's Disease (AD) is critical to the clinical development of targeted treatments. Neurodegeneration of the subiculum (SUB) is an early biomarker of AD, but it is unknown if specific SUB cell-types are susceptible to AD neurodegeneration. In the 5xFAD mouse model, significant cell loss occurs within the SUB by 8 months of age.

Financial Advice for Difficult Times: 2 Sides of a Coin.

This article invites 2 experts having knowledge of financial management: one from within the dental fraternity and one from outside to assist the orthodontists (academic and practitioners alike) to help provide some guidance to sail through these turbulent times. With the COVID-19 pandemic, we are witnessing an unprecedented moment in history that has impacted the entire globe at a never before seen scale. This coronavirus has resulted in a where there is a health and financial pandemic at the same time.