Knowledge, Attitudes, and Practice of Guided Dentistry Among Dental Personnel of North India: A Cross-Sectional Study.

Objective The aim of this study was to assess the knowledge and awareness of guided dentistry among various dental professionals.  Materials and methods The study was carried out as a cross-sectional descriptive observational study among dental professionals (students, practitioners, and teaching faculty in academic institutions) in North India. A web-based electronic survey using Google Forms was designed to obtain the responses of participants toward awareness of guided dentistry and its applications in dentistry.

In Silico Insights on GD2 : A Potential Target for Pediatric Neuroblastoma.

Background: Originating from the abnormal growth of neuroblasts, pediatric neuroblastoma affects the age group below 15 years. It is an aggressive heterogenous cancer with a high morbidity rate. Biological marker GD2 synthesised by the GD2 gene acts as a powerful predictor of neuroblastoma cells.

Design of novel JAK3 Inhibitors towards Rheumatoid Arthritis using molecular docking analysis.

Multiple cytokines play a pivotal role in the pathogenesis of Rheumatoid Arthritis by inducing intracellular signaling and it is known that the members of the Janus kinase (JAK) family are essential for such signal transduction. Janus kinase 3 is a tyrosine kinase that belongs to the Janus family of kinases. Drugs targeting JAK3 in the treatment of Rheumatoid arthritis is relevant.