Publications by authors named "Shreeya Bhonge"
Article Synopsis
- In neurodegenerative diseases, the shape and structure of β-sheet amyloids play a crucial role, with their chirality (left- or right-handed) affecting their function and disease onset.
- Researchers have studied the amyloid-β 42 sequence and created variations that allow for switching chirality at relevant body temperatures.
- This chiral inversion not only influences the amyloids but also enhances drug release for anticancer treatments, presenting a new way to modify amyloid shapes for potential therapies in neurodegenerative and other diseases.
