Publications by authors named "Shpil'kin V"

The authors compare the roentgenological findings with the parameters of contractility obtained during heart catheterization in 49 patients with mitral valvular disease and aortal valvular disease. The parameters are shown to be correlated with regard to the nature of valvular damage, characteristics of the impairment of the intracardiac hemodynamics and myocardial contractile function. Certain tendencies of this dependence are tabulated.

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Levels of PGE2, PGF2 alpha and renin activity were measured in renal venous blood of 29 patients with essential hypertension (EH), 23 patients with renovascular hypertension (RVH) and 10 patients with unilateral pyelonephritis and high arterial hypertension. The pattern of change in renal venous PG content was found to be related to the type of renal lesion: the level of PGE2 was lowered and PGF2 alpha/PGF2 ratio increased in the blood outflow from the kidneys of EH patients and from ischemized kidneys of RVH patients as compared to similar parameters in the outflow from contralateral kidneys of patients with RVH and pyelonephritis. Venous levels of both PGs were the highest in pyelonephritis-affected kidneys.

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In 20 patients with stenosis of the renal artery and arterial hypertension Gruentzig balloon catheter was introduced transcutaneously into the artery with subsequent dilatation. In 2 cases arterial pressure became normal, in 8 the course of the disease improved, in 4 high hypertension was retained but responded to hypotensive agents, in 2 there was no effect, and in 4 balloon dilatation could not be carried out due to the impossibility of pushing the catheter through the stenosed segment of vessel. According to the data of renal scintigraphy plasma flow on the affected side rose by 16-66% after dilatation as compared to the initial figures, there was no significant change in the contralateral kidney.

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It was found that hypertension in patients with stenosis of the renal artery is of a renopressor character which is maintained by increased renin secretion by the kidney with the stenosed artery. High arterial hypertension is conducive to the maintenance of the function of the kidney with the stenosed artery at the most optimum level and has an effect on the contralateral kidney. After surgery (nephrectomy), in addition to normalization of arterial pressure the blood flow in the remaining kidney becomes almost equal to the blood flow in two kidneys, i.

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The article discusses the results of the examination of 40 patients with symptomatic renal hypertension (in 15 of whom arterial hypertension followed a malignant course) and 19 patients with IIB-IIIA stages of hypertensive disease (6 of whom had the malignant form). Marked activation of the renin-angiotensin system along with reduced renal blood flow was found in patients with symptomatic renal hypertension. Despite the reduced renal blood flow, patients with the malignant form of hypertensive disease had diminished activity and secretion of renin as well as a considerably increased prostaglandin F2 alpha content and reduced sodium content in the plasma of renal venous and, particularly in the plasma of aortic blood.

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Separate renal blood flow was studied by the method of dye dilution (euviridine) in catheterization of the renal vessels during angiography. The method and techniques of catheterization of the arteries and veins and the sequence of manipulations in recording certain parameters of common and separate renal hemodynamics are described. The high informativeness of the method is shown and the complications which were encountered are described and discussed.

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