Predictive value of peripheral lymphocyte subsets for the disease progression in patients with sepsis.

Objective: To investigate the predictive value of peripheral lymphocyte subsets for sepsis progression.

Methods: Patients with sepsis were divided into the improved group (n = 46) and severe group (n = 39) according to disease progression. Flow cytometric analysis was performed to enumerate absolute counts of peripheral lymphocyte subsets.

Preparation of a novel bone wax with modified tricalcium silicate cement and BGs.

Amino-grafted and vaterite-contained tricalcium silicate cement (A-V-CS) was composited with 58S bioglass/chitosan/carboxy methyl cellulose (BG/CS/CMC, referred as BGs) to surmount the non-absorbability and infection problems of traditional bone wax. Its material, bioactive, biocompatible and antibacterial properties were systematically characterized. The results revealed that A-V-CS/BGs possessed self-setting, injectable, mechanical and degradable abilities.

Association of polymorphisms in ERAP1 and risk of ankylosing spondylitis in a Chinese population.

To explore the association between five polymorphisms in endoplasmic reticulum associated aminopeptidase 1 (ERAP1) gene and risk of ankylosing spondylitis (AS) in a Chinese population. A case-control study enrolled 250 AS patients and 250 healthy controls was carried out. The genotypes of involved polymorphisms (rs27037, rs27038, rs469876, rs27044 and rs27980) in ERAP1 were detected by Sequenom Mass-Array platform.