Publications by authors named "Shouxing Shen"
Article Synopsis
- Dysregulation of the ubiquitin-proteasome pathway is crucial for tumor growth, and shikonin, derived from traditional Chinese medicine, shows potential as a tumor cell-killer.
- This study found that shikonin inhibits proteasome activity both in lab settings and in live models, leading to the accumulation of pro-apoptotic proteins and promoting cell death in various cancer types.
- Additionally, shikonin treatment significantly retarded tumor growth in live animal models and improved survival rates in mice with leukemia, highlighting its potential as an effective anti-cancer therapy.
