Publications by authors named "Shouxi Pan"
Umbilical cord-derived mesenchymal stem cell membrane-loaded minoxidil (MXD) nanoparticles (STCM-MXD-NPs) were prepared to investigate their effects on hair growth in C57BL/6J mice. STCM-MXD-NPs were obtained by freeze-thawing and differential centrifugation, and their effects on hair growth were evaluated using C57BL/6J mice. The mRNA and protein expression levels of vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1) were detected by real-time polymerase chain reaction and enzyme-linked immunosorbent assays, respectively.
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- The study aimed to investigate the relationship between alpha1-antitrypsin (A1AT), pro-inflammatory cytokines, and other related factors in rats with polycystic ovary syndrome (PCOS).
- Female rats were divided into control and PCOS groups, with the latter receiving a high-fat diet and letrozole to induce PCOS, and various molecular analyses were conducted.
- Results showed that A1AT levels decreased in PCOS rats while neutrophil elastase (NE), IL-1β, and IL-8 levels increased, suggesting that A1AT may help reduce PCOS symptoms by targeting these inflammatory factors.