Publications by authors named "Shouthing Zhang"
Mol Cell Biol
February 2005
Article Synopsis
- Members of the TGF-beta and Wnt/wingless superfamilies play crucial roles in regulating cell fate during development and tissue maintenance.
- Smad7 interacts with beta-catenin and LEF1/TCF in a way that depends on TGF-beta, and it's necessary for the accumulation of these proteins in certain human cell types.
- Suppressing Smad7 hinders TGF-beta's effects, including preventing specific protein activations and the crucial association between beta-catenin and LEF1, which is linked to TGF-beta-induced apoptosis.
