Publications by authors named "Shouli Yi"
The aim of the present study was to establish a simple and reliable ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method and apply it for the determination of pharmacokinetics of moxidectin-loaded microspheres (MOX-MS) in rats. Plasma samples were processed using a simplified liquid-liquid extraction method and were separated using an Agilent Zorbax Eclipse Plus C18 column (50 mm × 2.1 mm, 1.
View Article and Find Full Text PDFUnder salt stress, recretohalophyte Plumbago auriculata tetraploids enhance salt tolerance by increasing selective secretion of Na compared with that in diploids, although the mechanism is unclear. Using non-invasive micro-test technology, the effect of salt gland Ca content on Na and K secretion were investigated in diploid and tetraploid P. auriculata under salt stress.
View Article and Find Full Text PDF"Heteromorphic self-incompatibility" (HetSI) in plants is a mechanism of defense to avoid self-pollination and promote outcrossing. However, the molecular mechanism underlying HetSI remains largely unknown. In this study, RNA-seq was conducted to explore the molecular mechanisms underlying self-compatible (SC, "T × P" and "P × T") and self-incompatible (SI, "T × T" and "P × P") pollination in the two types of flowers of Lam.
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- ACMP (Asparagus cochinchinensis polysaccharide) enhances the non-specific immune response of macrophages but its role in innate immune memory and histone modification hasn't been explored until now.
- The study investigates how ACMP affects macrophages by co-incubating it with RAW264.7 and BMDM cells, focusing on pattern recognition receptors (PRR) and changes in signaling pathways.
- Results show that ACMP activates the TLR4-MAPK signaling pathway, increases histone modifications (H3K4me1), and boosts immune-related gene responses, indicating that ACMP can induce innate immune memory in macrophages.
Article Synopsis
- - Ammonia and nitrite stress can weaken the immune system and cause oxidative stress, but treatment with Tian-Dong-Tang-Gan Powder (TDTGP) may enhance immunity and resistance to these stresses.
- - A study fed 3,000 subjects varying doses of TDTGP for 35 days, then exposed them to ammonia and nitrite for 72 hours while analyzing gene expression and gut microbiota changes.
- - TDTGP treatment increased the expression of genes linked to immunity and antioxidants, reduced harmful gut bacteria, and helped maintain a healthier gut microbiota balance, mitigating the negative effects of ammonia and nitrite stress.
Quercitrin is a kind of flavonoid that is found in many plants; it has good antioxidant activity, and can regulate oxidative stress induced by Pseudorabies virus (PRV)-infected cells. In this study, the secretion of reactive oxygen species (ROS) induced by PRV infection was detected by flow cytometry, and RNA expression profiles of the 3D4/2 cells were produced and analyzed by sequenced GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes); the sequencing results were verified by RT-qCR. The results showed that the secretion of ROS induced by PRV infection in 3D4/2 cells could be significantly decreased by quercitrin.
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