Publications by authors named "Shouichi Iida"
Ther Apher Dial
February 2011
Article Synopsis
- Spousal donor transplantation (SDT) generally has poorer histocompatibility and a higher risk of acute rejection (AR) compared to related donor transplantation (RDT), particularly due to HLA sensitization from pregnancy.
- In a study of 379 transplant cases, desensitization techniques including plasmapheresis and rituximab were used primarily for patients at high immunological risk, resulting in no significant difference in AR rates between SDT and RDT in that group.
- Preoperative rituximab significantly lowered AR rates and showed that with proper desensitization, SDT risks can be managed effectively, with similar five-year graft survival rates for both donor types.
