Effects of extract of Ginkgo biloba with venlafaxine on brain injury in a rat model of depression.

Background: Recent studies have indicated that chronic stress may give rise to brain damage, which is related to the genesis of depression. The purpose of this study is to investigate the effects of extract of Ginkgo biloba (EGb) and venlafaxine on depression.

Methods: Rats were treated with chronic and comprehensive stress to create a depression model.