Publications by authors named "Shou-Min Zhang"
Article Synopsis
- A study was conducted to evaluate a combination gel containing adapalene 0.1% and clindamycin 1% for treating moderate acne, comparing its effectiveness to each medication used alone.
- Results showed that the combination gel significantly reduced acne lesions by 66.85% after 12 weeks, outperforming adapalene (50.82%) and clindamycin (57.61%).
- The combination gel was well tolerated and resulted in more participants achieving a 2-grade improvement in acne severity, indicating it is a more effective treatment option than the individual monotherapies.
Compared with a single semiconductor, the heterojunction formed by two different semiconductors usually has higher light utilization and better photoelectric performance. By using stable TiO nanotubes as the main subject, CdSe/TiONTs heterojunctions were synthesized by a hydrothermal method. XRD, TEM, SEM, PL, UV-vis, and EIS were used to characterize the fabricated CdSe/TiONTs.
View Article and Find Full Text PDFThe formation of heterojunction structures can effectively prevent the recombination of photogenerated electron-hole pairs in semiconductors and result in the enhancement of photoelectric properties. Using TiO nanotubes (prepared using the hydrothermal-impregnation method) as carriers, CdS-TiONTs were fabricated as a photoelectrochemical (PEC) sensor, which can be used under visible light and can exhibit good PEC performance due to the existence of the heterojunction structure. The experimental results show that the prepared CdS-TiONTs electrode had a linear response to 2-16 mM glutathione (GSH).
View Article and Find Full Text PDFAutophagy is an adaptation mechanism to keep cellular homeostasis, and its deregulation is implicated in various cardiovascular diseases. After vein grafting, hemodynamic factors play crucial roles in neointimal hyperplasia, but the mechanisms are poorly understood. Here, we investigated the impacts of arterial cyclic stretch on autophagy of venous smooth muscle cells (SMCs) and its role in neointima formation after vein grafting.
View Article and Find Full Text PDFArticle Synopsis
- Vascular intimal injury leads to cardiovascular diseases by activating platelets and releasing collagen-activated microvesicles (aPMVs) that influence vascular smooth muscle cells (VSMCs).
- aPMVs alter VSMC energy metabolism, promoting excessive proliferation and migration, which contributes to neointimal hyperplasia.
- The study identifies the Pka-PRKAA-FoxO1 signaling pathway as a mechanism by which aPMVs impact VSMC function, suggesting potential targets for preventing abnormal VSMC activity after vascular injury.