[Accuracy evaluation of diagnostic test in laboratory].

The theory and application of ROC curve are briefly introduced in this paper. Three main ROC curve related indices, area under curve (AUC), partial area under curve (pAUC), and sensitivity at a particular false-positive-rate (1-specificity) [Se(FPR=e)], are used to analyze a real data of five hepatitis B surface agent kits with calculated steps and explanation, including the bootstrap method for statistical inference of these indices.

[A nested case control study for risk factors impacting hepatitis B vaccination in Hebei, China].

Objective: Study the risk factors that impact the effectiveness of mass hepatitis B vaccination, and try to amend them in the future.

Method: Based on the national surveillance of hepatitis B, all the 1734 of 1-15 years old children from Hebei Province were enrolled in the present study and they were divided into case and control group according to their sera HBsAg were positive or not.

Results: Mother sera HBsAg positive and the hospital the children were born and earlier year of birth were risk factors.

Long-term disability from acute childhood Japanese encephalitis in Shanghai, China.

We traced 85 Japanese encephalitis (JE) patients, 6-27 years after hospitalizations. The first control group was made up of 73 non-JE encephalitis patients 6-27 years previously, whereas the second control group was made up 78 neighborhood residents, matched to the 78 surviving JE cases by age, sex, and residence. All subjects were examined with neurologic examinations, intelligence quotient (IQ) measurement, Mini-Mental State Examinations (MMSE), and activities of daily living (ADL) assessments.

Incidence of diarrhea caused by rotavirus infections in rural Zhengding, China: prospective, population-based surveillance.

Rotavirus is the pathogen most commonly associated with severe gastroenteritis in young children in the People's Republic of China, yet there are few population-based data on the incidence of rotavirus infection. The present study investigated the burden of rotavirus diarrhea and rotavirus infections in rural China, according to age. Population-based surveillance was used to study the incidence of rotavirus infection among children <5 years of age in 4 townships of Zhengding County, Hebei Province, China.

[An effective method to reduce bias between two compared groups: propensity score].

Objective: Through introduction of principal theory and algorithm of propensity score to design SAS macro programs for binary data.

Methods: Propensity score method was used to compare the differences of character variables between two groups, and the association of DNR (Do Not Resuscitate) with the mortality of congestive heart failure was evaluated with different methods.

Results: Significant differences among the character variables between two groups were effectively balanced with stratification or matching method.