Publications by authors named "Shotaro Tsukamoto"
To report the status of switch rates and time-to-switch of antiretroviral therapy (ART) regimens by evaluating anchor drug classes and common switching patterns in Japanese people living with human immunodeficiency virus (HIV, PLWH). This cross-sectional cohort study extracted data of 28,089 PLWH from the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB), which contains data representing the entire population of Japan. PLWH with first prescription records of ART administered between January 2011 and March 2019 were identified (n = 16,069).
View Article and Find Full Text PDFObjectives: Comorbidities are associated with a high burden of disease in people living with HIV (PLWH). The objective was to investigate the prevalence of chronic comorbidities and use of co-medications in PLWH in Japan.
Methods: This study retrospectively analysed clinical information from PLWH receiving antiretroviral therapy (ART) between April 2009 and March 2019.
Article Synopsis
- * Analysis of the National Database of Health Insurance Claims reveals that 42.5% of newly diagnosed HIV-positive patients also had a diagnosis of syphilis between 2011 and 2018.
- * The findings indicate that many syphilis patients were not tested for HIV, and a notable number of HIV patients still contracted syphilis after their diagnosis, underlining the need for better education on STD testing for those newly diagnosed with HIV.
Aims: Pharmacotherapy for methamphetamine dependence has not yet been developed in Japan or elsewhere in the world. Ifenprodil is a blocker of G protein-activated inwardly rectifying potassium channels that play a key role in the mechanism of action of addictive substances. Our aim is to examine the safety, efficacy, and outcomes of ifenprodil for the treatment of methamphetamine dependence in a randomized, double-blind, placebo-controlled trial.
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