Publications by authors named "Shotaro Hosoda"
Obesity (Silver Spring)
April 2023
Article Synopsis
- The study explores the preventive effects of sodium ferrous citrate (SFC) and 5-aminolevulinic acid phosphate (ALA) on metabolic issues related to obesity and type 2 diabetes.
- The experiment involved feeding male mice different diets for 15 weeks, revealing that SFC and ALA combined improved muscle strength, reduced obesity, and helped maintain normal mitochondrial function.
- Results indicate that SFC and ALA supplementation could be a promising intervention for preventing metabolic disorders linked to obesity and type 2 diabetes by enhancing skeletal muscle and mitochondrial health.
Article Synopsis
- Iron metabolism disruptions are linked to metabolic diseases like obesity and liver fat accumulation, and iron deficiency is often seen in obese individuals.
- Iron supplementation in mice on a high-fat diet led to reduced weight gain and lower liver fat, while also improving mitochondrial health and function in both the liver and muscles.
- This study highlights how iron acts as a signaling molecule that enhances mitochondrial activity and energy metabolism, shedding light on its potential role in managing obesity and related liver conditions.
