Publications by authors named "Shorya Thakur"
Background: The genus Bauhinia and its species has been known since ages by tribal people and medicinal practitioners in tropical and subtropical regions for the treatment of diabetes, diarrhea, cough, fever, stomach disorders, skin diseases, and other diseases.
Study Design: Our aim was to collect and explore the literature available on the traditional applications and medicinal potential of genus Bauhinia across Asia, so that this review can be used as standard to analyze the immense potential of this genus and can be explored further for clinical use.
Methods: The information was rigorously gathered from Google Scholar, Pub Med, Elsevier, Wiley Online Search, Science Direct, and other literature sources.
Objective: In this review, we have summarized antifungal agents containing potent azole analogues.
Data Acquisition: The provided literature is related to the development and application of azole derivatives and has been accessed from electronic data bases such as Science direct, Google Scholar, and Pubmed using keywords such as "design, synthesis and evaluation", "azole hybrids", "diazole hybrids", "indazole derivatives", "imidazole derivatives", "triazole derivatives", "tetrazole derivatives" and related combinations.
Result: From this review, it was identified that azole derivatives with promising antifungal activity play a vital role in drug discovery and development.
Cystic fibrosis is a genetic disorder inherited in an autosomal recessive manner. It is caused by a mutation in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene on chromosome 7, which leads to abnormal regulation of chloride and bicarbonate ions in cells that line organs like the lungs and pancreas. The CFTR protein plays a crucial role in regulating chloride ion flow, and its absence or malfunction causes the production of thick mucus that affects several organs.
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