Kounis syndrome caused by protamine shock after coronary intervention: A case report.

We report a case of Kounis syndrome that led to shock after protamine administration during percutaneous coronary intervention (PCI). A man in his 50s was admitted to the nearest hospital following the onset of acute myocardial infarction. Coronary angiography showed a single-vessel lesion in the left anterior descending artery (LAD).

Impact of Water- and Lipid-Soluble Statins on Nonculprit Lesions in Patients with Acute Coronary Syndrome.

Statins can be differentiated into two types, based on their solubility, which have potentially differing effects on the coronary artery wall. However, suspected differences in statins' effects on plaque composition have not been systemically investigated.Sixty-seven patients with acute coronary syndrome (ACS) were randomly assigned to either atorvastatin (10 mg/day) or rosuvastatin (2.

Serial endovascular assessment of polytetrafluoroethylene-covered stent: Capabilities and limitations of intravascular imaging modalities affected by a temporal factor.

A 47-year-old male who previously underwent coronary bypass graft surgery was transferred to our hospital for treatment of bare metal in-stent restenosis (ISR) of severely calcified left main (LM) coronary lesion. During a repeat coronary intervention, LM coronary perforation occurred after rotational atherectomy followed by balloon dilatation. Hemostasis was successfully achieved by implantation of a single polytetrafluoroethylene (PTFE)-covered stent.

Morphological and quantitative analysis of vascular wall and neointimal hyperplasia after coronary stenting: comparison of bare-metal and sirolimus-eluting stents using optical coherence tomography.

Background: It has been suggested that sirolimus-eluting stents (SES) provoke a more sustained inflammatory response (IR) in neointimal hyperplasia (NIH). The purpose of this study was to compare morphological vessel characteristics, including post-stent IR in NIH, between patients with SES and bare metal stents (BMS) using optical coherence tomography (OCT).

Methods And Results: Thirty-seven patients underwent OCT at their post-stent follow-up.

Chronic thrombus occlusion after bare metal stenting in a patient with acute coronary syndrome visualized by optical coherence tomography.

We present a case of chronic thrombus occlusion visualized by optical coherence tomography (OCT) in a patient following bare metal stent (BMS) implantation. A 74-year-old Japanese man was treated with single BMS implantation for acute coronary syndrome. The second follow-up angiography demonstrated no restenosis at the BMS site in the convalescent phase before discharge.

Comparison of long-term prognostic evaluation between pre-intervention thrombolysis and primary coronary intervention: a prospective randomized trial: five-year results of the IMPORTANT study.

Background: Acute efficacy and long-term prognostic differences between ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (primary PCI) and those treated with pre-intervention thrombolysis combined with back-up of facilitated PCI has not been evaluated in Japanese patients. The purpose of the present study was therefore to evaluate the differences between treatment with primary PCI (primary-PCI group) and pre-treatment with tissue-type plasminogen activator (t-PA) combined with back-up of facilitated PCI (prior-t-PA group).

Methods And Results: One hundred and one patients with STEMI were randomly assigned to 2 groups.

Low-density lipoprotein-cholesterol/high-density lipoprotein-cholesterol ratio predicts lipid-rich coronary plaque in patients with coronary artery disease--integrated-backscatter intravascular ultrasound study.

Background: The relationship between blood lipid profile and coronary plaque tissue characteristics, and differences in the tissue characteristics between acute coronary syndrome (ACS) and chronic coronary artery disease (CCAD) are unclear. The purpose of the present study was to compare the plaque tissue characteristics in patients with ACS and CCAD and to examine the relationship between the tissue characteristics and blood lipid profile.

Methods And Results: Integrated backscatter intravascular ultrasound (IVUS) and conventional IVUS were performed in patients with ACS (n=24) and CCAD (n=68) at the time of coronary intervention.

Late stent thrombosis after discontinuation of dual anti-platelet therapy in off-label use of paclitaxel-eluting stent visualized by optical coherence tomography-3-vessel OCT study.

We observed late stent thrombosis image by optical coherence tomography (OCT) in vessels with off-label paclitaxel-eluting stents (PES) implantation. A 59-year-old Japanese man was treated with a single on-label PES for chronic coronary artery disease in the left circumflex artery. After 9 months, he was implanted with two linked PESs in the left anterior descending artery (LAD) and a single PES in the right coronary artery (RCA).

Peripheral vasodilatory dysfunction in adult patients with congenital heart disease and severely elevated pulmonary vascular resistance.

Several studies have demonstrated that pulmonary vascular abnormalities precede alterations in aortic circulation downstream in animal models of heart failure. The relationship between increased pulmonary vascular resistance (PVR) and agonist-induced limb vasodilatory response remains unknown in patients with congenital cardiovascular shunt lesions (CSL). The authors hypothesized that patients with CSL and severely elevated PVR will show a defective vasomotor response in the peripheral vascular bed.