Publications by authors named "Shola Able-Thomas"
Unlabelled: Timely diagnostic tools are needed to improve antibiotic treatment. Pairing metagenomic sequencing with genomic neighbor typing algorithms may support rapid clinically actionable results. We created resistance-associated sequence elements (RASE) databases for and .
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- This study compares the effectiveness of two DNA extraction kits (DNeasy PowerSoil Kit and DNeasy PowerLyzer PowerSoil Kit) in detecting pathogens from samples collected from the nasopharynx/oropharynx (NP/OP).
- Results showed that the PowerLyzer kit yielded higher DNA concentrations and better detection rates for pathogens like S. pneumoniae, H. influenzae, and N. meningitidis compared to the discontinued kit.
- The findings suggest that using the more efficient kit could improve the recovery of low-abundance bacteria in clinical settings, but researchers should consider potential Ct value discrepancies when comparing results across studies utilizing different kits.