Inborn Errors of Metabolism Associated With Autism Among Children: A Multicenter Study from Iran.

Objective: This study aimed to find the common inborn errors of metabolism in Iranian patients with autism spectrum disorder.

Methods: In this cross-sectional multicenter study, 105 children and adolescents with autism spectrum disorder from six centers in different cities of Iran were enrolled between August, 2019 and October, 2020. Metabolic screening, including measuring plasma levels of amino acids, acylcarnitines, creatine, and guani-dinoacetate, and urinary levels of organic acids, purines, and pyrimidines was performed.