Publications by authors named "Shoko Yamada"

The first step in treating diabetes mellitus (DM)-related diarrhea is to thoroughly control the serum glucose level. The authors herein describe a 75-year-old man who was diagnosed with type 1 DM when he was 32 years old. The patient lost his appetite due to hot weather and spent a week eating sweets and drinking juice.

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An 87-year-old woman was admitted to our hospital (day 0) because of acute disorientation caused by multiple acute intracerebral hemorrhages. T2*-weighted magnetic resonance imaging (MRI) at admission revealed multiple subcortical old microbleeds indicative of cerebral amyloid angiopathy. Microbleeds in the right cerebellar hemisphere and acute spotty ischemia in the left cerebellum were also identified.

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Article Synopsis
  • * Both patients initially showed signs of recovery but exhibited key symptoms like constipation, diarrhea, and abnormal lab results shortly before succumbing to NOMI.
  • * The article highlights the importance of early recognition of NOMI after minor head trauma, emphasizing that timely diagnosis could lead to surgical intervention and potentially save lives.
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Patients with a persistent primitive trigeminal artery frequently have a poorly developed vertebrobasilar arterial system. However, they are not at higher risk of stroke and most are asymptomatic. Left cerebral watershed infarction was identified in a 75-year-old man who presented with aphasia and disorientation on magnetic resonance image (MRI).

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  • Jasmonic acid (JA) is a plant hormone that regulates defense and development, and this study focuses on the MYB transcription factor JMTF1's role in rice's defense against bacterial blight caused by Xanthomonas oryzae.
  • Transgenic rice plants overexpressing JMTF1 exhibited a hypersensitive response to JA and showed increased resistance to the blight, partly by upregulating genes that contribute to lignin and antibacterial compound production.
  • JMTF1 also affected auxin signaling, leading to phenotypic changes in root and shoot development, while modulating the expression of auxin-responsive genes, indicating its role in balancing JA and auxin pathways for improved disease resistance.
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  • This study examined patients with subcortical hemorrhage to differentiate between those with cerebral amyloid angiopathy (CAA) and those with non-CAA (hypertensive) via histological diagnosis.
  • Out of 100 analyzed cases, the CAA group was notably older and had lower blood pressure but larger hematomas compared to the non-CAA group, with similar outcomes post-surgery.
  • While surgery for CAA-related hemorrhages is typically safe, factors like age over 80, intraventricular hemorrhage complications, large hematoma size, and pre-existing dementia were linked to increased mortality risks.
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Invited for the cover of this issue is the group of Koh Sugamata, Mao Minoura, and co-workers at Rikkyo University. The image depicts triptycene-based metal-organic frameworks with honeycomb structures that collect carbon dioxide and hydrogen, in an analogy to bees collecting honey in their honeycombs. Read the full text of the article at 10.

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It is not rare that progressive hydrocephalus worsens clinical conditions in a patient with external decompression and drainage or shunt surgery is required. However, spinal drainage or shunt surgeries potentially carry a risk of causing paradoxical herniation in a patient with decompressive craniectomy, particularly in a comatose case with wide craniectomy. Careful and strict observations are necessary for such patients.

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A series of metal-organic frameworks (MOFs) based on zinc ions and two triptycene ligands of different size have been synthesized under solvothermal conditions. Structural analyses revealed that they are isostructural 3D-network MOFs. The high porosity and thermal stability of these MOFs can be attributed to the highly rigid triptycene-based ligands.

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When using imaging to diagnose brain tumors, it is important to determine whether the tumor is intra- or extra-parenchymal. An 80-year-old man was found on magnetic resonance imaging to have an enhanced mass that appeared to be in the falx and a massive hematoma in the left frontal lobe; the provisional diagnosis was falx meningioma. However, the tumor and hematoma were found intraoperatively to be completely intraparenchymal.

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  • Immobile stroke patients experience decreased bone mineral density (BMD), especially in the proximal femur, with significant reduction observed in female patients over a two-month period.
  • A study measuring BMD and various serum and urine biomarkers in 100 stroke patients found no change in lumbar vertebrae BMD but a notable decrease in femoral BMD.
  • Further research is needed to confirm these findings and explore the underlying factors affecting BMD loss, as the differential effects might relate to physical forces and nutrition.
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infectious endocarditis has a high mortality, major causes of death being cardiac failure, systemic embolism, and sepsis. Pseudoaneurysms, a rare complication of this infection, are not invariably fatal with appropriate treatment. A previously healthy 32-year-old man was found to have multiple cerebral infarctions, and infectious endocarditis with mitral valve vegetation was diagnosed by echocardiography.

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Lymphomatosis cerebri is an atypical form of primary central nervous system lymphoma (PCNSL), which frequently causes rapid progression of dementia. A 68-year-old woman exhibited rapidly progressing disorientation and a mini-mental state examination score of 9. The fluid-attenuated inversion recovery of a magnetic resonance image (MRI) demonstrated focal areas of high-signal intensity in the right frontal lobe with a small enhancement, which was histologically diagnosed as diffuse large B-cell type lymphoma.

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  • - It can be tough to predict vasospasm in patients with traumatic subarachnoid hemorrhage (SAH), but factors like younger age, lower Glasgow coma scale scores, and more blood volume in the cisterns may increase the risk of it developing.
  • - Two cases of older patients (74 and 72 years) with traumatic SAH showed initial alertness but developed cognitive dysfunction shortly after due to vasospasm, which was linked to the presence of thick hemorrhage in follow-up imaging.
  • - The study emphasizes that the presence of focally thick traumatic SAH with poor clearance is a key factor for post-traumatic vasospasm, suggesting that prompt treatment should be initiated within three days to improve patient outcomes
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Background: Critically ill patients experience various types of pain that are difficult to assess because patients cannot communicate verbally due to artificial airways and sustained sedation. The Critical-Care Pain Observation Tool (CPOT) objectively evaluates patients' pain.

Aims: This study aimed to re-assess the reliability and validity of the Japanese version (CPOT-J) and to reveal limitations of behaviors specific to mechanically ventilated patients.

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Background: Diffuse midline glioma H3 K27M-mutant is a distinct subtype of glial tumors newly introduced in the revised fourth edition of the World Health Organization . They are aggressive pediatric tumors with a poor prognosis but have also been reported in adults.

Observations: The authors present the case of a man in his 60s who presented with rotatory vertigo, taste disorder, and right facial paralysis.

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In chronic subdural hematoma (CSDH) patients, motor functions usually recover quickly after burr-hole surgery; however, in a rare case, the hemiparesis showed poor improvement after surgery. In that case, investigation of cerebral infarctions is important. Among the 284 CSDH patients with motor weakness, magnetic resonance image (MRI) and MR angiography (MRA) were acquired in 82 patients before surgery when the hemiparesis progressed rapidly.

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Objective: Onabotulinum toxin A (botulinum A toxin) is utilized to extend flexed extremities in spastic hemiparesis. Injection points are important to obtain a better effect. Injecting botulinum A toxin into the forearm muscles is a standard method for flexed wrist and fingers; however, we developed new injection points in the intrinsic muscles of the hand to acquire more reliable effect.

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What Is Known And Objective: Perampanel, an anticonvulsant, might induce psychological reactions.

Case Description: A 70-year-old woman, who had been taking 2500 mg/day levetiracetam, complained of right-hand minor-convulsion. Perampanel of 2 mg/day was additionally prescribed, and the dosage was increased to 4 mg/day.

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Introduction: In cranioplasty, pinwheel-shaped titanium mini plates are frequently used to cover bone defects produced by burr holes, and it is common to insert screws through only a few of the holes in cranial flap fixation.

Presentation Of Case: A 69-year-old man who had undergone clipping surgery for subarachnoid hemorrhage 16 years previously visited our clinic because a titanium plate had penetrated his scalp one month after he was hit on the head by a wall cabinet. Imaging studies revealed that part of the titanium plate had bent outwards and penetrated the skin.

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Background: Hemiparesis is a major symptom of chronic subdural hematoma (CSDH). Its severity does not always correlate with hematoma size. The authors analyzed hematoma thickness, pressure, and tension to clarify the mechanism of hemiparesis in CSDH patients.

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Background: It is very rare but challenging to perform emergency airway management for accidental extubation in a patient whose head and neck are fixed in the prone position when urgently turning the patient to the supine position would be unsafe. The authors hypothesized that tracheal intubation with a videolaryngoscope would allow effective airway rescue in this situation compared with a supraglottic airway device and designed a randomized crossover manikin study to test this hypothesis.

Methods: The authors compared airway rescue performances of the 3 devices-the ProSeal laryngeal mask airway (PLMA; Teleflex Medical, Westmeath, Ireland) as a reference; the Pentax AWS (AWS; Nihon Kohden, Tokyo, Japan) as a channeled blade-type videolaryngoscope; and the McGRATH videolaryngoscope (McGRATH; Medtronic, Minneapolis, MN) as a nonchanneled blade type in a manikin fixed to the operating table in the prone position.

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Astroblastoma is a rare tumor that is thought to occur exclusively in the cerebrum. To the authors' knowledge, no cases of spinal cord astroblastoma have been reported. A 20-year-old woman presented with numbness in her legs.

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Headache is a major symptom in chronic subdural hematoma (CSDH) patients. However, some CSDH patients do not complain headache although the hematoma is thick with definite midline shift. This clinical study was performed to identify the mechanism of headache in CSDH patients.

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The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres.

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