Publications by authors named "Shoko Miyawaki"
Reproduction
October 2024
Article Synopsis
- Repro57 mice with a mutation in the Rnf212 gene are infertile, showing issues with sperm development in males and unclear infertility causes in females.
- In male mice, spermatogenesis is arrested, leading to the absence of mature sperm, while female mice show aneuploidy and altered chromosomal patterns in their oocytes.
- Although fertilization rates don’t significantly differ between wild-type and mutant mice, the mutant embryos struggle with later developmental stages, leading to lower success rates in forming morulae and blastocysts.
