Hierarchical-Porous Hollow Nitrogen-Doped Carbon-Supported Pt Alloy Catalysts with a Controllable Triheterointerface for Methanol Electrooxidation.

Carbon-supported Pt-based catalysts are the most effective catalysts for direct methanol fuel cells (DMFCs). However, challenges such as high Pt loading, cost, and susceptibility to CO poisoning severely hinder the development of DMFCs. In this paper, CoFeO@polymer@ZIF-67 is prepared successfully through sequential solution polymerization and in situ growth with modified CoFeO as the core.

Prospects for Treatment of Lung Cancer Using Activated Lymphocytes Combined with Other Anti-Cancer Modalities.

This review explores the significance and prospects of using diverse T-cell variants in the context of combined therapy for lung cancer treatment. Recently, there has been an increase in research focused on understanding the critical role of tumor-specific T lymphocytes and the potential benefits of autologous T-cell-based treatments for individuals with lung cancer. One promising approach involves intravenous administration of ex vivo-activated autologous lymphocytes to improve the immune status of patients with cancer.

Improving Fertility in Non-obstructive Azoospermia: Results from an Autologous Bone Mar-row-Derived Mesenchymal Stromal/Stem Cell Phase I Clinical Trial.

Background: In this phase I clinical trial, our primary objective was to develop an innovative therapeutic approach utilizing autologous bone marrow-derived mesenchymal stromal/stem cells (BM-MSCs) for the treatment of nonobstructive azoospermia (NOA). Additionally, we aimed to assess the feasibility and safety of this approach.

Materials And Methods: We recruited 80 participants in this non-randomized, open-label clinical trial, including patients undergoing NOA treatment using autologous BM-MSCs (n=40) and those receiving hormone therapy as a control group (n=40).

Dynamics of Sex Hormones in Men with Diabetes Mellitus After Autologous Mesenchymal Stem Cell Transplant.

Objectives: Our goal was to determine levels of sex hormones in men with type 1 diabetes mellitus and type 2 diabetes mellitus after autologous mesenchymal stem cell transplant.

Materials And Methods: We examined 10 male patients (32-56 years old) with type 1 diabetes mellitus and type 2 diabetes mellitus, whom we subsequently divided into 2 groups and examined. Group 1 comprised 5 male patients who received autologous mesenchymal stem cell transplant (cells were obtained from patient's iliac crest and cultured for 3-4 weeks) by intravenous infusion.

Public Health Response Measures for COVID-19 in Kazakhstan.

The article describes measures developed to counter the spread of coronavirus infection in the Republic of Kazakhstan. The first cases of coronavirus disease 2019 (COVID-19) in Kazakhstan were detected on March 13, 2020, among people who arrived from Germany. After declaring the state of emergency in the country, the Ministry of Healthcare of the Republic of Kazakhstan began to formulate and implement a comprehensive package of measures aimed at slowing down and stopping the transmission of infection, preventing outbreaks, ensuring optimal care for all patients, especially the seriously ill, minimizing the negative impact of the pandemic on health systems, social services, and economic activities.

Assessment of the Negative Impact of Urban Air Pollution on Population Health Using Machine Learning Method.

This study focuses on assessing the level of morbidity among the population of Almaty, Kazakhstan, and investigating its connection with atmospheric air pollution using machine learning algorithms. The use of these algorithms is aimed at analyzing the relationship between air pollution levels and the state of public health, as well as the correlations between COVID-19 infection and the development of respiratory diseases. This study analyzes the respiratory diseases of the population of Almaty and the level of air pollution as a result of suspended particles for the period of 2017-2022.

Experimental study on clinical and morphological determination of the optimal cannula diameter for lipoaspirate harvest from rabbit inguinal fat pad.

Determining the most appropriate cannula diameter for lipoaspirate harvesting is important, both in terms of the quality and composition of the material obtained, and the ease of practical use of the cannula. The size of the cannula is one of the main factors affecting the qualitative characteristics of the obtained lipoaspirate sample for further use of adipose tissue. The purpose of the investigation was to clinically and histomorphometrically determine the optimal cannula diameter for lipoaspirate samples collection from rabbit inguinal fat pad in an experimental study.

Health Status and Quality of Life in the Population near Zhezkazgan Copper Smelter, Kazakhstan.

Background: The industrial city of Zhezkazgan is one of the most important cities in the industrial sector and the most polluted city in the Republic of Kazakhstan. There is placed Kazakhstan's largest copper smelter. The entire technological process (extraction, crushing, grinding, purification, and smelting of pure ingots) of the production of the copper smelter releases into the environment mainly various kinds of solid particles, sulfur oxides (SOx), and various carcinogenic elements.

Influence of Mineralized Water Sources on the Properties of Calcisol and Yield of Wheat ( L.).

The use of conservation agriculture (SWC-soil and water conservation) technologies is now becoming more and more necessary. For the soils in arid ecosystems, the problem of irrigation deficiencies has always been relevant, and clean fresh water is always insufficient to irrigate these agricultural lands. This paper provides a brief historical overview of the use of mineralized water sources in agriculture and their impacts on soils and plants ( L.

Morphotype broadening of the grapevine (Vitis vinifera L.) from Oxus civilization 4000 BP, Central Asia.

The region of Transoxiana underwent an early agricultural-demographic transition leading to the earliest proto-urban centers in Central Asia. The agronomic details of this cultural shift are still poorly studied, especially regarding the role that long-generation perennials, such as grapes, played in the cultivation system. In this paper, we present directly dated remains of grape pips from the early urban centers of Sapalli and Djarkutan, in south Uzbekistan.

Predicting Mortality by Causes in the Republic of Bashkortostan Using the Lee-Carter Model.

This paper analyzes and predicts age-sex mortality rates by causes in the Republic of Bashkortostan. The following methods of analysis were used: the Lee-Carter model, singular value decomposition, and ARIMA-modeling. The forecast results suggest that by 2025 the Republic of Bashkortostan will have lower mortality due to malignant neoplasms in all age groups, except for the 70+ group for women and 50+ age groups for men; lower mortality due to diseases of the circulatory system in all age groups for men and higher mortality in 45+ age groups for women; lower mortality due to injuries in all age groups for both sexes; no significant changes in mortality due to respiratory diseases; increased mortality from gastrointestinal diseases for both sexes at all ages, except for children; higher mortality due to infections at 20-54 for men and 20-64 for women; and almost half lower mortality from infections in the age group of 0-4 years for both sexes.

Mesenchymal stromal/stem cells and their exosomes for restoration of spermatogenesis in non-obstructive azoospermia: a systemic review.

Stem cells have been introduced as new promising therapeutic agents in treatment of degenerative diseases because of having high differentiation potential while maintaining the ability to self-replicate and retaining features of their source cells. Among different type of cell therapies, mesenchymal stromal/stem cell (MSC) therapy is being increasingly developed as a new way to treat structural defects that need to be repaired and regenerated. Non-obstructive azoospermia (NOA) is a reproductive disease in men that causes infertility in 10% of infertile men.

[Inferior turbinate neoplasms].

Introduction: The main aim of the work was to describe a rare clinical case of osteoma of inferior turbinate. The interest of the case is that such tumors are extremely rare.

Results: A female patient of 63 years old attended an ENT clinic.

Cost-effective horse breeding in the Republic of Bashkortostan, Russia.

Background And Aim: There is a lack of reliable data in agribusiness regarding the economic efficiency of horse breeding, and this limits its further development. The purpose of this study was to create rational parameters for the development of productive horse breeding as an effective agricultural business, in particular, in relation to farms.

Materials And Methods: The methods of investigation used were induction and deduction, as well as analytical, statistical, and economic-mathematical analysis.

Strategic Planning of Rural Development Based on Foresight Methodologies.

The purpose of the study is to establish scientific rational for the use of the foresight methodology in the strategic planning of rural development. The scientific novelty of the study is determined by the development of an algorithm for strategic planning of rural development based on the foresight methodology and by the formation of a set of practical recommendations for the use of foresight tools at the municipal level of management in rural areas. The paper states that modern foresight methodology is quite flexible and multifaceted.

[The effect of medical economic factors on common morbidity of population of the Republic of Bashkortostan].

The assessment was applied to degree of impact of medical social factors on morbidity of total population according appealability in the Republic of Bashkortostan, considering their spatial temporal distribution. The database of the Federal Information Fund for Social and Hygienic Monitoring (Automated Information System "Social and Hygienic Monitoring") of the Department of Rospotrebnadzor and data of official statistical forms of the Territorial Board of the Federal State Statistics Service in the Republic of Bashkortostan were used as source material for the study. The data was applied in case of presence of combination of observations on 54 municipalities and 8 urban okrugs in the dynamics for 2000-2015.

[The trends in disability of adult and children population of the Republic of Bashkortostan in 2000-2015].

The article considers dynamics and main indices of primary and total disability of adult and children population in the regions in 2005-2015 as compared to similar indices of the Russian Federation on the basis of the data of Medical Informational Analytical Center of the Ministry of Health Care of the Republic of Bashkortostan, the territorial Agency of Federal Service of State statistics of the Republic of Bashkortostan. The characteristics of indices and their dynamics, structure of leading causes of disability of adult and children population and differences in levels of disability were established. The established tendencies of dynamics of indices of disability in the Republic of Bashkortostan can be taken as a principle in development of programs of prevention of disability and rehabilitation of disable individuals.

Autologous Mesenchymal Stem Cell Transplant in Patients with Type 1 Diabetes Mellitus.

Objectives: Our goal was to determine the efficacy of autologous mesenchymal stem cell transplant for treatment in patients with type 1 diabetes mellitus.

Materials And Methods: We examined 5 patients (4 male, 1 female; age 20-42 y) with type 1 diabetes mellitus who received autologous mesenchymal stem cell transplant (cells were obtained from the patient's iliac crest and cultured for 3-4 weeks) performed by intravenous infusion. The quantity of autologous mesenchymal stem cells infused was 95 to 97 × 106.

Integral Hematologic Indices in the Evaluation of the Immunologic Reactivity of the Organism in a Patient With Complication of Type 1 Diabetes Mellitus: A Case of Diabetic Retinopathy After Autologous Mesenchymal Stem Cell Transplant.

The search continues for pathogenetically effective measures in autoimmune processes for a number of complications of type 1 diabetes mellitus, in particular, diabetic retinopathy. However, there are few studies of the prognostic and therapeutic values of the systemic autoimmune response in this pathology after transplant of autologous mesenchymal stem cells. Here, we present a 40-year-old patient with complications of type 1 diabetes mellitus (diabetic retinopathy) after mesenchymal stem cell transplant.

Infusion of autologous bone marrow derived mononuclear stem cells potentially reduces urinary markers in diabetic nephropathy.

Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Previous studies demonstrated safety and efficacy of autologous bone marrow-derived mononuclear cells (ABM-MNCs) in induced type-1 diabetes mellitus (T1DM) rats. However, the effect of ABM-MNCs on urinary markers of DN in humans is not well studied.

[The dynamics of mortality because of diseases of blood circulation system in the regions of the Republic of Bashkortostan].

The article presents analysis of level, dynamics and structure of mortality of diseases of blood circulation system in the regions of the Republic of Bashkortostan according to data of the Territorial board of Federal service of state statistics in the Republic of Bashkortostan in 2002-2012 (table C-51). The differences are established in the levels of mortality as compared with the Republic ofBashkortostan and the Russian Federation. Despite of outlined tendency of decreasing of levels of mortality because of the given cause, it continues to be sufficiently high and requires further investigation of all its aspects.

[EVALUATION OF THE AIR POLLUTION HEALTH RISK FOR THE POPULATION OF THE CITY OF UFA].

There are presented results of the calculation of carcinogenic and non-carcinogenic risks due to the impact of chemical air pollutants for the human health of a large industrial city. Maximal levels of carcinogenic hazards under inhalation route of substances from the air were established to be noted on gasoline, manganese, sulfur dioxide, copper oxide, formaldehyde. In the formation of carcinogenic risk the greatest contribution is made by chromium, gasoline, formaldehyde, benzol.

[The dynamics of mortality of population of able-bodied age in the Republic of Bashkortostan].

The article analyzes data of state statistics concerning mortality of able-bodied population (table C51) in the regions of the Republic of Bashkortostan in 2002-201. The structure of main causes of death is analyzed. The comparative analysis of received data and analogous indicators in the Republic of Bashkortostan and Russia was carried out.