Publications by authors named "Shoji Okado"

We present a case of robot-assisted complex anatomical segmentectomy utilizing Resection Process Map (RPM) software. RPM enables the confirmation of internal structures obscured by lung parenchyma, thereby reducing the risk of injury or misidentification to essential structures. It facilitates an accurate understanding of anatomy beyond processed vessels, fostering collaboration among the surgical team and informed discussions.

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A 55-year-old woman with no significant medical history or symptoms was incidentally diagnosed with a mediastinal tumor during a routine health checkup. The intraoperative findings of robot-assisted thoracoscopic surgery led to the diagnosis of extralobar pulmonary sequestration (EPS), with multiple vessels connecting to the pulmonary artery and superior pulmonary vein. EPS, an extremely rare condition, is typically supplied with blood from the aorta.

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Peribronchiolar metaplasia is an uncommon lesion characterized by fibrosis and bronchiolar epithelial cell proliferation along the peribronchiolar alveolar walls, primarily in response to bronchiolar and peribronchiolar injuries. Peribronchiolar metaplasia usually appears as ground glass nodules or sub-solid nodules on computed tomography. However, we present an exceptional case of peribronchiolar metaplasia that appeared as a solitary solid nodule on computed tomography.

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Article Synopsis
  • Researchers have developed a computer system that generates virtual thoracoscopic images from preoperative CT scans to help locate small pulmonary nodules before lung surgery.
  • This method simulates the lung's position and requires only the CT images to determine the nodule's location, potentially avoiding complications linked to traditional localization techniques.
  • Early results show that virtual images closely match real thoracoscopic views, though the study is still in its preliminary phase and has some limitations.
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  • Postoperative air leakage is the most common complication after surgery for lung tumors, leading to longer hospital stays and increased costs.
  • This study analyzed air leaks during and after robotic-assisted thoracic surgery (RATS) compared to video-assisted thoracic surgery (VATS) from 2018 to 2022, focusing on their incidence and causes.
  • Results showed that RATS had a significantly higher rate of persistent and unexpected air leaks compared to VATS, although both procedures had similar hospital stay durations.
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Background: Nuclear protein in testis (NUT) carcinoma (NC) of the lung is a rare cancer that occurs mainly in young adolescents and adults. NC is genetically characterized by rearrangements, which usually take the form of fusions. The prognosis for NC is dismal, and treatment with conventional chemotherapeutic regimens is ineffective.

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Article Synopsis
  • A new minimally invasive treatment for pneumothorax has been developed using a super-thin catheter that injects fibrin glue to close air leaks in lungs, demonstrating effective results in pig lung studies.
  • The method involved creating artificial pneumothorax and testing the catheter's ability to stop air leaks, achieving a high success rate of 90.5% in experiments, with no significant complications noted.
  • This innovative approach could transform pneumothorax treatment, leading toward human trials and improved patient outcomes.
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Background/aim: Immune checkpoint inhibitors (ICIs) have been widely used in the treatment of non-small cell lung cancer (NSCLC), but specific outcomes of ICIs treatment among patients with postoperative recurrence of NSCLC remain unclear. The objective of the study was to compare the efficacy of ICIs and chemotherapy with conventional chemotherapy only in patients with postoperative recurrence of epidermal growth factor receptor (EGFR) wild-type NSCLC.

Patients And Methods: A retrospective analysis was performed on patients who underwent anatomical lung resection at the Nagoya University Hospital and were treated for postoperative recurrence of wild-type EGFR NSCLC.

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Background: A multidisciplinary treatment approach is recommended for patients with extensive, advanced, or recurrent thymomas. However, detailed treatment strategies, such as chemotherapy regimens and optimal surgical procedures, are still under debate.

Case Presentation: We report a case of gigantic locally advanced thymoma.

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Malignant pleural mesothelioma (MPM) develops primarily from asbestos exposures and has a poor prognosis. In this study, The Cancer Genome Atlas was used to perform a comprehensive survival analysis, which identified the gene as a potential predictor of favorable overall survival for patients with MPM. An enrichment analysis of favorable prognostic genes, including , showed immune-related ontological terms, whereas an analysis of unfavorable prognostic genes indicated cell-cycle-related terms.

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Article Synopsis
  • Accurate identification of lung segments is crucial during segmentectomy, and Indocyanine Green (ICG) aids in this visualization.
  • A study analyzed 111 cases of lung segmentectomy from April 2020 to March 2023, finding that most (94%) had clear segment boundaries while 6% had unclear boundaries, which were linked to lower pulmonary function measurements (DLCO).
  • The unclear boundary cases were all lower lobe segmentectomies, suggesting that patients with lower DLCO values faced more challenges in accurately identifying intersegmental planes.
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Background: Taste disorders in patients with thymoma accompanied by myasthenia gravis (MG) is rare.

Case Description: The first case was a male in his 50s who underwent surgery for Masaoka stage III type B3 thymoma. He experienced a loss of taste before surgery, which showed no improvement after surgery.

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While open window thoracostomy is used to treat empyema with a high rate of infection control, it is an invasive procedure that leads to a decline in the quality of life. An 80-year-old man who had undergone wedge resection for pulmonary nodules subsequently developed postoperative empyema and underwent open window thoracostomy. After thoracostomy, the patient developed several complications, including bleeding from the lung surface and air leakage.

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Background: Preoperative three-dimensional (3D) computed tomography (CT) images have been widely used as surgical guides in lung surgery; however, the lungs tend to be deflated during surgery. Discrepancies between the preoperatively constructed 3D image and the intraoperative view of the deflated lungs often require preoperative and/or intraoperative marking methods for sublobar pulmonary resection. We have developed a lung deflation simulation algorithm in which 3D CT images of the deflated lungs can be predicted only based on the preoperative CT taken in an inflated phase of respiration.

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Background: Based on computed tomography (CT) findings of lung cancer, solid nodules have a much worse prognosis than subsolid nodules, even if the nodules are subcentimeter in size. There is, however, no systematic method for determining the prognosis of solid tumors on CT. This study aimed to discover the prognostic factor of early-stage solid lung adenocarcinoma using three-dimensional CT volumetry.

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Lingular-segment torsion after left-upper division segmentectomy (LUDS) is a rare complication, and the cause remains unclear. Here we report the case of a patient who developed lingular-segment torsion after LUDS for multiple lung metastases of breast cancer. One lung nodule was located in the S1 + 2 segment and another between the upper lobe and S6 on an incomplete interlobar fissure.

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Background: The COVID-19 pandemic has affected the clinical practice of lung cancer surgery in Japan, but few studies have revealed the real situation of surgical practice for lung cancer in this country. This latest information will help us to decide the future direction of lung cancer surgery under pandemic circumstances.

Methods: We collected data from patients with primary lung cancer who underwent thoracic surgery between 2018 and 2021.

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