Publications by authors named "Shohre Khatami"
Coronavirus disease 2019 (COVID-19) can present with a variety of symptoms. Severity of the disease may be associated with several factors. Here, we review clinical features of COVID-19 inpatients with different severities.
View Article and Find Full Text PDFBackground: Coronavirus disease 2019 (COVID-19) has rapidly emerged as a threatening pandemic. Clinical features of this pandemic involve a wide range of manifestations and are not completely known. Here, we present six cases of thrombotic events in patients with COVID-19.
View Article and Find Full Text PDFBackground: Regarding the role of gut microbial dysbiosis in hyperglycemia, we aimed to compare the main gut bacterial composition among type 1 and type 2 diabetic patients and healthy non-diabetic adults.
Methods: A total of 110 adult subjects (49 patients diagnosed with type 2 diabetes, 21 patients diagnosed with type 1 diabetes and 40 healthy persons) were included in this case-control study. The intestinal microbiota composition was investigated by quantitative real-time polymerase chain reaction (qPCR) method targeting bacterial 16S rRNA gene.
Article Synopsis
- Probiotics can help improve gut health and metabolism related to obesity by altering the gut microbiota and maintaining mucosal barrier integrity.
- The study examined the effects of probiotics and their extracellular vesicles (EVs) on obesity-related genes using assays in both cell lines and C57BL/6 mice.
- Results indicated that EVs were more effective than the probiotics alone in reducing body and fat weight, enhancing lipid metabolism, and improving inflammation markers and blood parameters in high-fat diet-fed mice.
Comparative study of effect of and its extracellular vesicles on toll-like receptors and tight junction.
Gastroenterol Hepatol Bed Bench
January 2019
Aim: We assessed effect of and its extracellular vesicles on toll-like receptors and tight junction expression in human epithelial colorectal adenocarcinoma cells (Caco-2).
Background: The intestinal microbiota plays an important role in the intestinal homeostasis through its metabolites and derivatives. Interacting with immune cells and intestinal epithelial pattern recognition receptors (PRRs), intestinal microbiota regulates the function of the digestive barrier and inflammation caused by the metabolic diseases.