Publications by authors named "Shohei Sano"
Clinical outcomes over 2 years following arthroscopic ankle lateral ligament repair with os subfibulare.
Asia Pac J Sports Med Arthrosc Rehabil Technol
January 2025
Article Synopsis
- The study investigates the outcomes of arthroscopic lateral ligament repair for chronic lateral ankle instability (CLAI) in patients with and without an os subfibulare, a bone fragment that can complicate treatment; 33 patients (39 ankles) were tracked for over 2 years post-surgery.* -
- Results indicated significant improvements in both groups for overall foot function and related symptoms, as measured by the Japanese Society for Surgery of the Foot (JSSF) scale and the Self-administered Foot Evaluation Questionnaire (SAFE-Q), with no major differences between the ossicle and non-ossicle groups.* -
- In the group with os subfibulare, only 14.3% achieved bone union post-surgery,
Article Synopsis
- Distal femoral osteotomy (DFO) is a complex surgery for correcting deformities in the distal femur of patients with osteoarthritis, often performed alongside high tibial osteotomy (HTO).
- The study analyzed CT images of patients to understand the shapes and angles of the distal femur's cortices in different knee deformities (valgus and varus).
- Findings revealed significant differences in the medial and lateral cortical angles and heights, emphasizing that surgeons need to consider these morphological variations when conducting DFO to ensure successful outcomes.
Article Synopsis
- This study investigates risk factors for adverse events in patients with metastatic pancreatic cancer treated with a combination of nanoliposomal irinotecan, 5-fluorouracil, and L-leucovorin (nal-IRI/FL).
- It focuses on the UGT1A1 polymorphism, finding that patients with the homozygous variant (UGT1A1*6 or *28 (+/+)) experience lower white blood cell and neutrophil counts.
- Other identified risk factors for decreased white blood cell counts include high aspartate aminotransferase (AST) levels before therapy and being diagnosed with pancreatic head cancer.
Introduction: Osteogenesis imperfecta (OI) is a heritable disorder of connective tissue. Due to poor bone quality, patients with OI develop bone fracture and subsequent non-union at high rates. We report the rare case of humeral shaft non-union successfully treated by a locking plate used formandibular bone in a patient with OI.
View Article and Find Full Text PDFWe investigated the effects of treatment with trimethyltin (TMT) on the expression of glutathione-related enzymes in mouse hippocampus. TMT promoted the expression of glutathione S-transferase (GST) Ya/Yc mRNA, and GSTA2 protein, but not that of glutamate-cysteine ligase catalytic subunit mRNA, 1 day after injection. TMT produced a slight but significant elevation of GST activity during the period from day 1 to 7 post-treatment.
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