Publications by authors named "Shoana Quinn"
Article Synopsis
- Pediatric ulcerative colitis (UC) is generally diagnosed more severely in children than in adults, and tofacitinib, a medication used since 2018, has limited data on its effectiveness for this age group.
- A retrospective study examined the outcomes of tofacitinib treatment at a national center in Ireland, analyzing clinical characteristics and response over time in pediatric patients with UC.
- Of 15 children studied, 8 achieved clinical remission after starting tofacitinib, showing a significant decrease in Pediatric Ulcerative Colitis Activity Index (PUCAI) scores from baseline, with no notable differences in outcomes between those receiving it alone versus those on a combination of therapies.
Background: Outcomes in pediatric ulcerative colitis (UC) are heterogeneous and predictors of disease course eagerly sought. Mucosal atrophy (MA) is characterized by histological abnormalities of colonic intestinal glands.
Objective: To determine the prevalence of MA in a national inception cohort of pediatric UC and its impact on outcomes.
Cerebral Palsy (CP) describes a heterogenous group of non-progressive disorders of posture or movement, causing activity limitation, due to a lesion in the developing brain. CP is an umbrella term for a heterogenous condition and is, therefore, descriptive rather than a diagnosis. Each case requires detailed consideration of etiology.
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