Publications by authors named "Sho Takaoka"

Article Synopsis
  • Orbital apex syndrome (OAS) causes visual loss, double vision, and eye pain due to various underlying conditions, including acute invasive fungal rhinosinusitis (AIFRS).
  • A case study presented a 76-year-old man with OAS linked to AIFRS, who underwent surgery and received antifungal treatment after a failed corticosteroid regimen.
  • The findings highlight the difficulty in differentiating between AIFRS-induced OAS and other forms, emphasizing the importance of conducting a biopsy before corticosteroid treatment to avoid worsening fungal infections and ensure better patient outcomes.
View Article and Find Full Text PDF

Mesenchymal stem cells are an ideal source for regenerative medicine. For clinical use, cell culture should be done at stable conditions, thus the use of serum should be avoided because of the batch-to-batch variations of serum. Although several kinds of serum-free media are available, a method to confirm whether they contain serum has not been established yet.

View Article and Find Full Text PDF

We showed previously that a rigid and fibrous-structured cationic coiled-coil artificial protein had cell-penetrating activity that was significantly greater when compared with a less-structured cell-penetrating peptide. Nanomaterials with anisotropic structures often show aspect-ratio-dependent unique physicochemical properties, as well as cell-penetrating activities. In this report, we have designed and demonstrated the cell-penetrating activity of a shorter cationic coiled-coil protein.

View Article and Find Full Text PDF