Publications by authors named "Sho Kazui"

Aim: The present study aimed to investigate the impact of mild tricuspid regurgitation (TR) on the exercise capacity or clinical outcomes in patients with chronic heart failure (CHF).

Methods And Results: The study enrolled 511 patients with CHF who underwent cardiopulmonary exercise testing (CPET) between 2013 and 2018. The primary outcome was a composite of heart failure hospitalization and death.

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  • * The study analyzed the relationship between levels of inflammatory biomarkers and coronary plaque characteristics in 30 patients who underwent a procedure called percutaneous coronary intervention (PCI).
  • * Findings showed that a higher coronary plaque risk score (CPRS) was significantly associated with TLR and that serum levels of monocyte chemoattractant protein-1 (MCP-1) correlated with CPRS, suggesting it could help identify severe coronary plaque conditions.
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Background: The differences in pre- and early post-procedural blood flow dynamics between the two major types of bioprosthetic valves, the balloon-expandable valve (BEV) and self-expandable valve (SEV), in patients with aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR), have not been investigated. We aimed to investigate the differences in blood flow dynamics between the BEV and SEV using four-dimensional flow cardiovascular magnetic resonance (4D flow CMR).

Methods: We prospectively examined 98 consecutive patients with severe AS who underwent TAVR between May 2018 and November 2021 (58 BEV and 40 SEV) after excluding those without CMR because of a contraindication, inadequate imaging from the analyses, or patients' refusal.

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  • - The study investigated the link between long-term cardiac troponin levels and adverse events in patients with cardiac sarcoidosis who were treated with prednisolone, involving 63 patients and 463 troponin measurements over about 30 months.
  • - Results indicated that a higher cumulative level of troponin over time correlated with a greater risk of serious heart-related issues, such as ventricular tachycardia or sudden cardiac death, occurring in about 19% of patients.
  • - The findings suggest that monitoring troponin levels regularly could help identify patients at higher risk for adverse cardiac events, indicating its potential value in clinical settings.
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Several liver fibrotic markers are associated with prognosis in patients with heart failure (HF). However, the optimal markers for outcome prediction remain unclear. This study aimed to simultaneously investigate the prognostic value of liver fibrotic markers and the associations between these markers and clinical parameters in patients with HF without organic liver disease.

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The prognostic impact of peak workload-to-weight ratio (PWR) during cardiopulmonary exercise testing (CPET) and its determinants in patients with chronic heart failure (CHF) are not well understood. Consecutive 514 patients with CHF referred for CPET at the Hokkaido University Hospital between 2013 and 2018 were identified. The primary outcome was a composite of hospitalization because of worsening heart failure and death.

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