Key Determinants of Immediate Postoperative Pain, Nausea, and Vomiting in Orthognathic Surgery: Insights From a Retrospective Cohort Study.

Introduction Orthognathic surgery frequently leads to immediate postoperative pain (IPP) and postoperative nausea and vomiting (PONV), impacting patient recovery and satisfaction. This study aims to identify key determinants contributing to IPP and PONV following orthognathic surgery. Methods A retrospective cohort study was conducted involving patients who underwent orthognathic surgery at Kurume University Hospital between January 2020 and December 2023.

What prognostic factors have impacted the efficacy of immune checkpoint inhibitors in patients with recurrent or metastatic oral cancer?

Background: Immune checkpoint inhibitors (ICIs) are widely adapted for recurrent or metastatic head and neck cancer (RM-HNC), and various studies on its prognostic factors have been reported. We aimed to elucidate the prognostic factors of ICI treatment for RM oral cancer (RM-OC) in a retrospective study.

Methods: We retrospectively reviewed patients with RM-OC treated with ICIs (nivolumab and pembrolizumab) at our department from May 2017 to February 2023.

The CRK14 gene encoding a cysteine-rich receptor-like kinase is implicated in the regulation of global proliferative arrest in Arabidopsis thaliana.

Global proliferative arrest (GPA) is a phenomenon in monocarpic plants in which the activity of all aboveground meristems generally ceases in a nearly coordinated manner after the formation of a certain number of fruits. Despite the fact that GPA is a biologically and agriculturally important event, the underlying molecular mechanisms are not well understood. In this study, we attempted to elucidate the molecular mechanism of GPA regulation by identifying the gene responsible for the Arabidopsis mutant fireworks (fiw), causing an early GPA phenotype.

Multimodal flexible sensor for healthcare systems.

This paper describes potential applications of our previously developed fabric sensor into wearable healthcare or nursing systems based on its sensing modalities. This sensor is knitted from tension-sensitive electro-conductive yarns; whose structure has an elastic core, wound around by two separated tension-sensitive electro-conductive threads. This makes the sensor inherently flexible and stretchable, allowing it to conform to any complicated surface.

Analysis of post-exposure density growth in radiochromic film with respect to the radiation dose.

The post-exposure density growth (PEDG) is one of the characteristics of radiochromic film (RCF). In film dosimetry using RCF and a flatbed scanner, pixel values read out from the RCF are converted to dose (hereafter, film dose) by using a calibration curve. The aim of this study is to analyze the relationship between the pixel value read out from the RCF and the PEDG, and that between the film dose converted from the RCF and the PEDG.