Factors Affecting Outcomes of Stereoacuity in Partially Refractive Accommodative Esotropia with Motor Success Treated by Preoperative Prism Correction and Surgery.

Purpose: Favorable stereoacuity does not develop in all patients with partially refractive accommodative esotropia (PRAET) successfully aligned, and there have been few previous reports on the factors influencing stereoacuity outcomes in patients with PRAET treated with prismatic correction (PPC) and/or surgery. This study aimed to analyze factors affecting stereoacuity outcomes in patients of PRAET treated with PPC and surgery.

Study Design: Retrospective study.

Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5.

Normal receptor tyrosine kinases (RTKs) need to reach the plasma membrane (PM) for ligand-induced activation, whereas its cancer-causing mutants can be activated before reaching the PM in organelles, such as the Golgi/trans-Golgi network (TGN). Inhibitors of protein export from the endoplasmic reticulum (ER), such as brefeldin A (BFA) and 2-methylcoprophilinamide (M-COPA), can suppress the activation of mutant RTKs in cancer cells, suggesting that RTK mutants cannot initiate signaling in the ER. BFA and M-COPA block the function of ADP-ribosylation factors (ARFs) that play a crucial role in ER-Golgi protein trafficking.

Accuracy and Correlation of the Kinect-Based Semi-Automatic Scoring Method for Measuring Anomalous Head Posture as Compared to the CROM Device.

Objective: To determine the reliability of the Kinect-based semi-automatic scoring method (KSSM) using Kinect for Windows v2 for head posture compared to the cervical range-of-motion (CROM) device.

Methods And Analysis: Head positions between -40° and +40° of chin up/down (X), head turn (Y), and lateral tilt (Z) were measured in 10° increments in healthy volunteers. Their head positions were simultaneously measured using the KSSM and CROM.