Publications by authors named "Shizhu Lin"
Article Synopsis
- Probiotics, particularly from yogurt, may help improve sleep quality and reduce disturbances among adults, as suggested by a study analyzing data from over 49,000 participants in the National Health and Nutrition Examination Survey (NHANES).
- About 14% of the participants consumed yogurt or probiotic supplements, with findings indicating that this group had a lower prevalence of sleep disorders compared to those who did not consume these foods.
- The study highlights significant associations between probiotic intake and better sleep outcomes, especially in certain demographics such as males and individuals with normal BMI, indicating that including yogurt in the diet could be beneficial for sleep health.
General anesthesia alters the diversity and composition of the lung microbiota in rat.
Biomed Pharmacother
October 2023
Background: The lung microbiome plays a crucial role in human health and disease. Extensive studies have demonstrated that the disturbance of the lung microbiome influences immune response, cognition, and behavior. The goal of this study was to investigate the effect of general anesthetics on lung microbiome.
View Article and Find Full Text PDFTo investigate the correlation between NPPB gene variants and pulse pressure hypertension and the underlying regulatory mechanisms and try to confirm that NPPB may be a potential molecular target of gene therapy for pulse pressure hypertension. A total of 898 participants were recruited from the First Affiliated Hospital of Fujian Medical University and the plasmids with differential expression of NPPB were constructed. Genotype distribution of NPPB(rs3753581, rs198388, and rs198389)was analyzed and the expression of N-terminal pro-B-type natriuretic peptide(NT-proBNP) and renin-angiotensin -aldosterone system(RAAS) related indicators were identified in the groups studied.
View Article and Find Full Text PDFArticle Synopsis
- A new ultrasound-guided protocol for stellate ganglion block in rats significantly improves accuracy and reduces complications compared to traditional blind techniques.
- The study involved 56 rats divided into two groups, with one group receiving the block using ultrasound and the other using a blind injection method, and it measured outcomes like effective volume and complication rates.
- Results showed that the ultrasound-guided method required less lidocaine (0.040 ml) compared to the blind method (0.639 ml) and had a much lower incidence of complications, particularly regarding the brachial plexus and vagus nerve.
Introduction: Postoperative impaired sleep quality and pain are associated with adverse outcomes. Stellate ganglion block (SGB) has shown promising results in enhancing sleep quality and alleviating neuropathic pain. This study aimed to investigate the effects of ultrasound-guided SGB on postoperative sleep quality and pain in patients undergoing breast cancer surgery.
View Article and Find Full Text PDFBackground: Sleep deprivation (SD) often leads to complex detrimental consequences, though the mechanisms underlying these dysfunctional effects remain largely unknown. We investigated whether the right stellate ganglion block in rats can improve the spatial learning and memory dysfunction induced by sleep deprivation by alleviating the damage of hippocampus in rats.
Methods: Sixty four male Sprague Dawley rats were randomly divided into four groups: Control, SD (sleep deprivation), SGB (stellate ganglion block) and SGB + SD (stellate ganglion block+ sleep deprivation) (n = 16).
Background: Sleep deprivation (SD) has become a serious concern worldwide. This study aimed to identify key modules and candidate hub genes correlated with diseases caused by SD, using co-expression analysis.
Methods: The weighted gene co-expression network analysis was performed to construct a co-expression network of hub genes correlated with SD.