Publications by authors named "Shiyue Wang"

Article Synopsis
  • Intracerebral calcium deposition includes primary familial brain calcification (PFBC), which leads to motor decline, speech difficulties, and cognitive issues, with limited treatment options available.* -
  • Recent findings link PFBC to blood-brain barrier dysfunction, influenced by genetic variants that affect the neurovascular unit (NVU), leading to brain calcification.* -
  • The review examines literature on genetic mutations in cell junction proteins related to brain calcification, aiming to identify molecular pathways and support the need for molecular subtyping in understanding this condition.*
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A new species of nematode, n.sp., parasite of the genus , is described based on specimens recovered from the small intestine of Leach, 1822 (Chiroptera: Vespertilionidae) in Longmen County, Guangdong Province, China.

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ESG (Environmental, Social and Governance) management practice is an important part of promoting sustainable operation and development of manufacturing enterprises. Currently, traditional evaluation methods have limitations such as low efficiency and lack of objectivity. To improve the efficiency and accuracy of ESG evaluation and promote the optimization of ESG performance in manufacturing enterprises, this article combined data mining and analytic hierarchy process (AHP) to conduct effective research on ESG management practice evaluation in manufacturing enterprises.

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Optofluidic techniques have evolved as a prospering strategy for microparticle manipulation via fluid. Unfortunately, there is still a lack of manipulation with simple preparation, easy operation, and multifunctional integration. In this Letter, we present an optofluidic device based on a graphite oxide (GO)-coated dual-fiber structure for multifunctional particle manipulation.

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Although outdoor air pollution has been associated with adverse health outcomes and decreased subjective welfare, there has been a lack of research investigating the potential risks associated with indoor unclean cooking energy usage from the perspective of subjective wellbeing. This paper systematically assesses the risks of unclean cooking fuel usage from the novel perspective of subjective welfare and examines the mediating role of perceived physical and mental health applying a large-scale nationally representative dataset. Analytical results demonstrate that the usage of unclean cooking energy has significantly negative impacts on subjective wellbeing, and this finding has been confirmed through various robustness tests.

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This paper describes a framework allowing intraoperative photoacoustic (PA) imaging integrated into minimally invasive surgical systems. PA is an emerging imaging modality that combines the high penetration of ultrasound (US) imaging with high optical contrast. With PA imaging, a surgical robot can provide intraoperative neurovascular guidance to the operating physician, alerting them of the presence of vital substrate anatomy invisible to the naked eye, preventing complications such as hemorrhage and paralysis.

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Background: In the present study, we measured the serum vascular endothelial cadherin (VEC) and vinculin (Vcn) concentrations in patients with type B acute aortic dissection (TBAD) to evaluate their diagnostic value for this condition.

Methods: A total of 100 patients with TBAD and 90 matched controls were included in the study. The serum concentrations of VEC and Vcn were measured using enzyme-linked immunosorbent assays.

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Background: Lipoprotein(a) [Lp(a)] is one of the residual risk factors for cardiovascular disease (CVD) in the setting of optimal low-density lipoprotein cholesterol (LDL-C). The association between Lp(a) and CVD is still in the exploratory phase, with few studies indicating a causal connection between Lp(a) and various CVD.

Methods: Lp(a) (n = 377,590) was a genome-wide association study (GWAS) based on European populations from Neale Lab.

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Article Synopsis
  • This study explored how abdominal aortic calcification affects the extent and blood supply during acute aortic dissection (AAD) in patients.
  • Conducted from August 2014 to May 2021, the research classified patients into three groups based on their calcification levels: no, low, and high calcification, finding that calcification influenced the prevalence of coronary heart disease and blood supply patterns.
  • The results showed that higher calcification grades were linked to a reduced extent of AAD, with significant implications for the management and prognosis of affected patients, though there were no notable differences in mid-term outcomes among the groups.
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Aim: To establish a fast, sensitive and accurate high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for determining the monosaccharide content of Qingzhuan Dark Tea polysaccharides in different years (2 years, 5 years and 11 years).

Methods: The optimised chromatographic conditions were achieved on a C18 column (5.0 μm, 250 mm × 4.

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Increasing evidence shows that the pathogenesis of Kawasaki disease (KD) is caused by abnormal and unbalanced innate and adaptive immune responses. However, the changes in and functions of adaptive immune cells in the peripheral blood of subjects with KD remain controversial. In this study, three different methods, CIBERSORT, Immune Cell Abundance Identifier (ImmuCellAI), and immune cell markers, were used to evaluate the proportions and abundances of immune cells in eight KD datasets (GSE9863, GSE9864, GSE18606, GSE63881, GSE68004, GSE73461, GSE73463, and GSE64486; a total of 1,251 samples).

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: It remains largely unclear about the function of 5-methylcytosine (m5C) RNA modification in the context of abdominal aortic aneurysm (AAA). In this regard, the present work focused on investigating m5C RNA methylation and related modulator expression levels in AAA. : To this end, we quantified the m5C methylation levels in AAA tissues (n = 32) and normal aortic tissues (n = 12) to examine the mRNA m5C status and m5C modulator expression at mRNA and protein levels.

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Background: m6A methylation-related long non-coding RNAs (lncRNAs) play a significant role in the progression of various tumors and can be used as prognostic markers. However, whether m6A-related lncRNAs also play the same function as prognostic markers in papillary thyroid carcinoma (PTC) remains unclear.

Methods: Consensus cluster analysis was performed to divide PTC samples obtained from The Cancer Genome Atlas database into two clusters according to the expression of m6A-related lncRNAs.

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Background: Ferroptosis is an iron-dependent and regulated cell death that has been widely reported in a variety of malignancies. The overall survival of papillary thyroid cancer (PTC) is excellent, but the identification of patients with poor prognosis still faces challenges. Nevertheless, whether ferroptosis-related genes (FRGs) can be used to screen high-risk patients is not clear.

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Objective: The present study investigated the differences in clinical characteristics, treatments, and outcomes of patients with acute aortic dissection (AAD) in different age groups.

Methods: The present single-center retrospective study was conducted from August 2014 to August 2020. The patients were divided into three groups: age <45 years (young group), age 45 to 59 years (middle-age group), and age >59 years (elderly group).

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Background: Triggering receptor expressed on myeloid cells-1 (TREM-1) has been reported as a biomarker in many cancers. However, the biological function of TREM-1 in papillary thyroid carcinoma (PTC) remains unknown.

Methods: We obtained TREM-1 expression data from The Cancer Genome Atlas (TCGA) database.

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Background: Interleukin-1 receptor antagonist (IL1RN) has been reported as a biomarker of many cancers. However, the biological function of IL1RN in papillary thyroid carcinoma (PTC) remains undetermined.

Methods: We obtained IL1RN expression data from The Cancer Genome Atlas (TCGA) database.

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Background: Papillary thyroid cancer has been associated with chronic inflammation. A systematic understanding of immune cell infiltration in PTC is essential for subsequent immune research and new diagnostic and therapeutic strategies.

Methods: Three different algorithms, single-sample gene set enrichment analysis (ssGSEA), immune cell marker and CIBERSORT, were used to evaluate immune cell infiltration levels (abundance and proportion) in 10 data sets (The Cancer Genome Atlas [TCGA], GSE3467, GSE3678, GSE5364, GSE27155, GSE33630, GSE50901, GSE53157, GSE58545, and GSE60542; a total of 799 PTC and 194 normal thyroid samples).

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Background: Tumor mutation burden (TMB) as a prognostic marker for immunotherapy has shown prognostic value in many cancers. However, there is no systematic investigation on TMB in papillary thyroid carcinoma (PTC).

Methods: Based on the somatic mutation data of 487 PTC patients from The Cancer Genome Atlas (TCGA), TMB was calculated, and we classified the samples into high-TMB (H-TMB) and low-TMB (L-TMB) groups.

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Background: has been recently reported as a biomarker in many cancers. However, a systematic investigation of in papillary thyroid carcinoma (PTC) has not been conducted.

Results: is overexpressed in PTC tissues and could be an independent prognostic factor.

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Objectives: This study was a systematic review of available data from China, and our aim was to evaluate the safety and efficacy of stenting in iliac vein compression syndrome.

Methods: We searched the PubMed, National Knowledge Infrastructure, Chongqing Weipu Information Company, and Cochrane Central Register for Controlled Trials databases, and key references.

Results: Twelve studies were included (nine retrospective analyses, two retrospective case series studies, and one prospective cohort study) involving 2292 patients and 1897 stented limbs.

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Background: Kallistatin (KS), encoded by , was suggested to play a protective role in many cardiovascular diseases. However, its role in the pathogenesis of abdominal aortic aneurysm (AAA) remains unclear. The aim of this study was to examine the potential association of KS with AAA pathogenesis.

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Abdominal aortic aneurysms (AAA) are life-threatening serious conditions that require effective and quick management. Although it is generally acknowledged that patients with AAA obtain the greatest benefit from endovascular repair (EVAR) compared to open surgical repair (OSR), there are few comparisons between the surgical approaches in Western versus Chinese patients. We aimed to perform a meta-analysis of studies in which EVAR was compared with OSR in the management of abdominal aortic aneurysms.

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Background: The role of N6-methyladenosine (m6A) modification in abdominal aortic aneurysm (AAA) has not been extensively studied. This study therefore aimed to investigate m6A RNA methylation and the expressions of the corresponding modulators in AAA.

Methods: A comparative study between AAA tissue samples (n=32) and healthy aortas (n=12) was performed using m6A methylation quantification for messenger RNA (mRNA) m6A status, quantitative polymerase chain reaction (qPCR), and western blot for the expressions of m6A modulators and immunohistochemistry (IHC) to detect locations of the modulators in AAA tissues.

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As a key environmental parameter to induce radiation dose and effect on non-human species, radioactivity level is rarely evaluated in typical ecosystems of coral reefs, mangroves, and hydrothermal vents. In this study, naturally occurring radionuclides (U, Ra, Ra, and K) in carbonate, silicate, and sulfide sediments collected from coral reefs, mangroves, and hydrothermal vents were simultaneously measured using high purity germanium (HPGe) γ spectrometry. Radioactivity levels and radionuclide fingerprints (Ra/U and Ra/Ra) were interpreted and explored for tracking sources and formation processes of marine sediments in distinct marine ecosystems.

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