Synopsis of recent research by authors named "Shiyu Shen"
- Shiyu Shen's recent research encompasses a diverse range of topics, primarily focusing on the interplay between inflammation, microglial function, and depression, highlighting the role of mitochondrial-associated membranes and various signaling pathways in the pathophysiology of depressive disorders.
- Significant findings include the identification of the PPAR-γ-mediated suppression of the NFκB signaling pathway in the antidepressant effects of rutin, as well as the exploration of the complement C1q/C3-CR3 signaling pathway that mediates microglial phagocytosis of synapses in animal models of depression.
- Additionally, Shen's research extends to clinical studies, such as the evaluation of imaging features in pediatric pulmonary nodules and the development of a questionnaire for assessing sedentary behavior in nursing students, indicating a broad commitment to both basic and applied medical research.
