Publications by authors named "Shiyu Pu"

Thermoelectric (TE) materials can convert the heat produced during biochemical reactions into electrical signals, enabling the self-powered detection of biomarkers. In this work, we design and fabricate a simple AgSe nanofilm-based TE biosensor to precisely quantify hydrogen peroxide (HO) levels in liquid samples. A chemical reaction involving horseradish peroxidase, ABTS and HO in the specimens produces a photothermal agent-ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) free radical, which triggers the heat fluctuations at the TE sensor through the photo-thermal effect, eventually enabling the sensing of HO.

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Skin is critical for shaping our interactions with the environment. The electronic skin (E-skin) has emerged as a promising interface for medical devices to replicate the functions of damaged skin. However, exploration of thermal perception, which is crucial for physiological sensing, has been limited.

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Article Synopsis
  • This study aimed to enhance the delivery of the VEGF gene to the hearts of rats using a method called ultrasound-mediated microbubble destruction (UMMD).
  • Fifteen male Wistar rats were divided into three groups after a heart procedure, with two groups receiving injections of VEGF gene via microbubbles, either with or without ultrasound assistance.
  • Results showed that the rats treated with UMMD had significantly increased levels of VEGF protein and new blood vessel formation in the damaged heart area compared to those who did not receive this treatment.
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