Fine mapping of a major co-localized QTL associated with self-incompatibility identified in two F populations (broccoli × cauliflower and cauliflower × Chinese kale).

A major QTL responsible for self-incompatibility was stably identified in two F populations. Through fine mapping and qRT-PCR analysis, ARK3 emerged as the most promising candidate gene, playing a pivotal role in regulating self-incompatibility in Brassica oleracea. Self-incompatibility (SI) is a common phenomenon in Brassica oleracea species, which can maintain genetic diversity but will also limit seed production.

Functional Validation of Different Alternative Splicing Variants of the Gene in Tobacco.

The Asteraceae are widely distributed throughout the world, with diverse functions and large genomes. Many of these genes remain undiscovered and unstudied. In this study, we discovered a new gene in and studied its function.

High resolution and large measurement range voltage sensing based on an optoelectronic oscillator utilizing an unbalanced Mach-Zehnder interferometer.

A voltage sensor with high resolution and large measurement range based on an optoelectronic oscillator (OEO) is proposed and experimentally demonstrated. The key component in the cavity to select the oscillating signal is a finite impulse response (FIR)-microwave photonic filter (MPF) which consists of a sinusoidal broadband optical signal, an unbalanced Mach-Zehnder interferometer (MZI), a section of dispersion compensating fiber, and a photodetector. The center frequency of the FIR-MPF is mainly determined by the free spectral range (FSR) of the FIR-MPF.

Simultaneous magnetic field and temperature measurement with high resolution based on cascaded microwave photonic filters.

A simultaneous magnetic field and temperature sensing scheme based on cascaded microwave photonic filters (MPFs) with high resolution is proposed and experimentally demonstrated. A polarization maintaining fiber bonded with a giant magnetostrictive material acts both as a magnetic field sensing probe and an important unit of a dispersion-induced MPF. A 500 m single mode fiber in a two-tap MPF is used to perform temperature compensation.

Alternative Splicing for Contributes to Variable Abiotic Stress Resistance in Transgenic Tobacco.

is a marsh plant in the family Compositae. It has good water and moisture resistance and ornamental properties, which makes it one of the important materials for chrysanthemum breeding and genetic improvement. The ( secondary wall enhancement factor 1) gene is associated with the thickening of the secondary walls of fiber cells in the plant ducts and the secondary xylem and plays an important role in plant stress resistance.

Simultaneous modulation format identification and OSNR monitoring based on optoelectronic reservoir computing.

An approach for simultaneous modulation format identification (MFI) and optical signal-to-noise ratio (OSNR) monitoring in digital coherent optical communications is proposed based on optoelectronic reservoir computing (RC) and the signal's amplitude histograms (AHs) obtained after the adaptive post-equalization. The optoelectronic RC is implemented using a Mach-Zehnder modulator and optoelectronic delay feedback loop. We investigate the performance of the proposed model with the number of symbols, bins of AHs and the hyperparameters of optoelectronic RC.

Enhanced performance of a reservoir computing system based on a dual-loop optoelectronic oscillator.

Time-delayed reservoir computing (RC) is a brain inspired paradigm for processing temporal information, with simplification in the network's architecture using virtual nodes embedded in a temporal delay line. In this work, a novel, to the best of our knowledge, RC system based on a dual-loop optoelectronic oscillator is proposed to enhance the prediction and classification. The hardware is compact and easy to implement, and only a section of fiber compared to the traditional optoelectronic oscillator reservoir is added to conform the dual-loop scheme.

Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.

Objectives: Evidences demonstrate that sorafenib alleviates liver fibrosis via inhibiting HSC activation and ECM accumulation. The underlying mechanism remains unclear. Ferroptosis, a novel programmed cell death, regulates diverse physiological/pathological processes.

Carvacrol alleviates liver fibrosis by inhibiting TRPM7 and modulating the MAPK signaling pathway.

Liver fibrosis is a compensatory response to the tissue repair process. The activation and proliferation of hepatic stellate cells (HSCs) are thought to be related to the occurrence of hepatic fibrosis. Therefore, inhibiting the activation and proliferation of HSCs is a key step in alleviating liver fibrosis.

PD-1/PD-L1 enhanced cisplatin resistance in gastric cancer through PI3K/AKT mediated P-gp expression.

Background: Programmed cell death receptor 1 (PD-1) is an immunosuppressive molecule expressed on T cells, and its ligand (PD-L1) which expressed on tumor cells play pivotal roles in regulating host immune responses. However, little is known whether PD-1/PD-L1 axis could directly activates intracellular oncogenic signaling pathways in tumor cells, leading to tumor resistance.

Methods: In the present study, the expression of PD-1 and PD-L1 in the tissues of gastric cancer was detected by western blot and immunofluorescence.

TRPM7 modulates macrophage polarization by STAT1/STAT6 pathways in RAW264.7 cells.

Macrophages, diversity and plasticity immune cells, participate in immune response and maintain homeostasis through M1/M2 phenotype transformation. Transient receptor potential melastatin 7 (TRPM7) is a widely expressed divalent cation channel with protein serine/threonine kinase activity, which has recently been found to affect macrophage proliferation and function. This study aimed to identify the role of TRPM7 in macrophage polarization.

Graphene quantum dots to enhance the photocatalytic hydrogen evolution efficiency of anatase TiO2 with exposed {001} facet.

Hydrogen evolution through photocatalysis is promising with respect to the environmental problems and challenges of energy shortage that we encounter today. In this paper, we have combined graphene quantum dots (GQDs) and {001} faceted anatase TiO2 (with an exposed percentage of 65-75%) together for effective photocatalytic hydrogen evolution. A series of characterizations including X-ray diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy and UV-visible absorption spectroscopy have been carried out to study the structure of the as-prepared GQDs/{001}TiO2 composite.

[Effects and mechanisms of punicosides on acute alcoholic liver damage in mice].

Objective: To evaluate the protective effects of punicosides on alcohol induced acute liver injury in mice and its possible mechanisms as well.

Method: The 60 mice were randomly divided into normal control, model group, three dose groups of punicosides with low, medium and high, then there is silibinin group. Three dose groups of punicosides and silibinin were given in advance by gavage for 4 weeks, then the mouse model of alcoholic acute liver injury was established.