A new luminescent nickel nanocluster with solvent and ion induced emission enhancement toward heavy metal analysis.

Expanding the family of fluorescent metal clusters beyond gold, silver, and copper has always been an issue for researchers to solve. In this study, a novel type of cysteine-capped nickel nanoclusters (Cys-Ni NCs) with bright turquoise emission was developed. The as-synthesized Ni NCs showed aggregation-induced emission enhancement (AIEE) properties across Cd and various polar organic solvents.

Total flavonoids of inhibit colonic barrier injury induced by acute pancreatitis by affecting gut microorganisms.

Background: Acute pancreatitis (AP) is a prevalent acute abdominal condition, and AP induced colonic barrier dysfunction is commonly observed. Total flavonoids of (TFC) have exhibited noteworthy anti-inflammatory and anti-apoptotic properties.

Methods: We established AP models, both in animals and cell cultures, employing Cerulein.

Comprehensive online two-dimensional liquid chromatography coupled to hybrid linear ion trap Orbitrap mass spectrometry with optimized dilution and modulation for analysis of Huangqi Guizhi Wuwu decoction.

Huangqi Guizhi Wuwu decoction (HGWD), as a classical formula, has been used for thousands of years in China. In this work, a comprehensive strategy was proposed for characterizing the chemical profile of HGWD based on online two-dimensional hydrophilic interaction and reversed-phase liquid chromatography coupled with hybrid linear ion trap-Orbitrap mass spectrometry (online HILIC × RP-ESI/HRMS/MS). The compounds in HGWD were first separated by the combined use of an XBridge amide column (150 × 4.

Multi-functional chitosan-based nanoparticles for drug delivery: Recent advanced insight into cancer therapy.

Cancer therapy continues to be a major global concern, with conventional treatments suffering from low efficacy, untargeted drug delivery, and severe side effects. Recent research in nanomedicine suggests that nanoparticles' unique physicochemical properties can be leveraged to surmount the limitations of conventional cancer treatment. Chitosan-based nanoparticles have gained significant attention due to their high drug-carrying capacity, non-toxicity, biocompatibility, and long circulation time.

Systematic evaluation and meta-analysis of Chinese medicine in the treatment of centrally mediated abdominal pain syndrome.

Background: This study aimed to evaluate the clinical efficacy of Chinese medicine for the treatment of centrally mediated abdominal pain syndrome (CAPS) using a meta-analysis system.

Methods: Six databases, including China National Knowledge Infrastructure, Vendor Information Pages, Chinese Biomedical Database, Wanfang, PubMed, and Embase were searched for randomized controlled trials related to the treatment of CAPS with traditional Chinese medicine. The bias risk assessment tool and RevMan5.

Spectrum-Effect Relationships of Flavonoids in Fisch.

Fisch. is used in large quantities in traditional Chinese medicine. It contains flavonoids, saponins, and polysaccharides, with flavonoids being the main active ingredients.

Cyclodextrin-based adsorbents for the removal of pollutants from wastewater: a review.

Water is a vital substance that constitutes biological structures and sustains life. However, water pollution is currently among the major environmental challenges and has attracted increasing study attention. How to handle contaminated water now mainly focuses on removing or reducing the pollutants from the wastewater.

Chemical and physical chitosan hydrogels as prospective carriers for drug delivery: a review.

With the advancement of medical research, the source and preparation of biological materials have gradually attracted attention. Hydrogels prepared from natural polysaccharides have been extensively applied in the medical field. The biocompatibility, excellent degradability and low toxicity of chitosan have favored the use of chitosan hydrogels as prospective carriers for drug delivery.

Dichloromethane extraction from Piper nigrum L. and P. longum L. to mitigate ischemic stroke by activating the AKT/mTOR signaling pathway to suppress autophagy.

Dichloromethane fraction (DF) of Piper nigrum L. and P. longum L.

Cyclodextrin-based delivery systems for chemotherapeutic anticancer drugs: A review.

Cancer is increasingly becoming a serious threat to human life and health. Therefore, the development of safe and effective therapeutic agents against the disease is of crucial significance. Cyclodextrins (CDs) are cyclic oligosaccharides obtained by the enzymatic hydrolysis of starch, and constitute a class of cyclic oligosaccharides with external hydrophilic and internal hydrophobic properties and have been used widely in cancer therapy.

Piperine as a neuroprotective functional component in rats with cerebral ischemic injury.

Long pepper ( L.) and black pepper ( L.) plants are commonly used as spices around the world and have also been postulated to have medicinal effects.

Neuroprotective Effect of Dichloromethane Extraction From Piper nigrum L. and Piper longum L. on Permanent Focal Cerebral Ischemia Injury in Rats.

Background: Piper nigrum L. and Piper longum L. consist a classic formula in traditional Chinese Hui medicine and are widely used in treatment of stroke.

The ethnopharmacology, phytochemistry and pharmacology of Angelica biserrata - A review.

Ethnopharmacological Relevance: Angelica biserrata (R.H. Shan & C.

Quality evaluation for Radix Astragali based on fingerprint, indicative components selection and QAMS.

Radix Astragali (RA) is one of the most widely used Chinese herbs prescribed in many Chinese formulas to reinforce 'Qi' and treat vital energy deficiency. This study combined fingerprinting with quantitative analysis multi-components by a single marker (QAMS) to improve the quality control standard for RA on the basis of existing quality control methods of traditional Chinese medicinal materials. UPLC-ESI-TOF-MS technique was used to evaluate the quality of RA by fingerprinting and QAMS.

Anti-inflammatory effect of Calycosin glycoside on lipopolysaccharide-induced inflammatory responses in RAW 264.7 cells.

Objective to find the Calycosin glycoside (CG) potential anti-inflammatory effect. The anti-inflammatory activity of CG was evaluated by lipopolysaccharide (LPS)-induced RAW 264.7 cells, and the IL-6, IL-1β, TNF-α and PGE2 level were measured by ELISA; NO levels in the culture media were determined using the Griess reaction.

Ethnomedicine, Phytochemistry and Pharmacology of Smilax glabra: An Important Traditional Chinese Medicine.

Smilax glabra (SG) Roxb., a well-known traditional Chinese medicine, has been extensively used worldwide for its marked pharmacological activities for treating syphilitic poisoned sores, limb hypertonicity, morbid leucorrhea, eczema pruritus, strangury due to heat, carbuncle toxin, and many other human ailments. Approximately 200 chemical compounds have been isolated from SG Roxb.