Novel mechanism by which extracellular vesicles derived from Lactobacillus murinus alleviates deoxynivalenol-induced intestinal barrier disruption.

Deoxynivalenol (DON) is a common environmental pollutant that poses a serious health risk to humans worldwide. This study was aim to explore whether gut microbiota is involved in DON-induced intestinal toxicity as well as to reveal effect of probiotics derived from gut microbiota in protecting intestinal barrier and to elucidate mechanism. We found that DON caused disturbed gut microbiota, particularly Lactobacillus murinus (L.

Antiaging Effects of Urolithin A on Replicative Senescent Human Skin Fibroblasts.

Although the health benefits attributed to urolithin A, such as anticancer, anti-inflammatory, and antioxidant effects, are based on numerous, diverse studies carried out , the biological effects of urolith A are still not entirely understood. In this study, we explored the biological effects of urolithin A using senescent human skin fibroblasts (HSFs) to determine whether urolithin A has any antiaging potential. Our results showed that urolithin A significantly increased type I collagen expression and reduced matrix metalloproteinase 1 (MMP-1) expression.

Pd-catalysed direct dehydrogenative carboxylation of alkenes: facile synthesis of vinyl esters.

A novel Pd-catalysed oxidative coupling reaction methodology using readily available carboxylic acids and alkenes for the preparation of vinyl esters has been developed. A broad range of vinyl esters were successfully synthesised. The reactions have demonstrated good efficiency as well as excellent chemo- and regio-selectivity.

Comparison of deformation texture in FePd alloy via X-ray diffraction and electron backscatter diffraction techniques.

In this work, textures measured by electron backscatter diffraction (EBSD) and X-ray diffraction in rolled FePd alloys were compared. The effect of scanning size used for EBSD measurements was investigated. The correlation coefficient was first proposed to quantify the similarity of the orientation density profile along the α- and β-fibers after cold rolling.