To evaluate the role of lactate dehydrogenase as biomarker in the progression of potentially malignant disorders in smokers and gutkha chewers.

Aim: To evaluate the role of lactate dehydrogenase (LDH) as a biomarker in the progression of potentially malignant disorders in smokers and gutkha chewers.

Material And Methods: The total of 70 individuals having the habit of chewing gutkha and smoking were selected for the study and divided into four groups. Group 1: 20 individuals having the habit of smoking, Group 2: 20 individuals having the habit of chewing gutkha, Group 3: 20 individuals having the habit of smoking and gutkha chewing, and Group 4: 10 healthy individuals.

Correlation Between Histological Grading and Ploidy Status in Oral Leukoplakia, Oral Submucous Fibrosis, and Oral Squamous Cell Carcinoma: A Flow Cytometric Analysis.

Background: Methods to analyze progression of carcinogenesis and stage of cancer are vital nowadays due to the high prevalence of these lesions. DNA ploidy analysis is one such important method in early diagnosis and improving prognosis.

Aims And Objectives: The aim of this study was to correlate histopathological grading and DNA ploidy in oral leukoplakia, oral submucous fibrosis (OSMF), and oral squamous cell carcinoma (OSCC) cases.