efficacy of 2% povidone iodine, chlorhexidine gluconate, and herbal extract mouthwash on SARS-CoV-2 viral load in saliva: A randomized clinical trial.

Background: One of the major techniques to reduce the transmission rate of COVID-19 would be to decrease the viral titers of SARS-CoV-2 in the saliva of infected patients and it is particularly useful in a dental setting. The present study evaluated the change in salivary viral load of COVID-19 patients using povidone iodine (PI), chlorhexidine (CHX), and an herbal extract (RightSure) oral antiviral herbal mouthwash (HM) at clinically recommended duration and concentrations.

Materials And Methods: Thirty individuals with SARS-CoV-2 were randomly allocated to three groups: (1) Group 1, PI mouthwash; (2) Group 2, CHX mouthwash; and (3) Group 3, HM mouthwash.

: A phytomedicine for local drug delivery - A strategic intervention.

Background: In the Indian system of medicine (ISM) is one of the oldest and longest used natural herbal remedy which consist of mixture of equal parts of the Gaertn. (Family- Euphorbiaceae), Retz. (Family- Combretaceae) and Terminalia beleria [Gaertn.

Diode laser therapy in the management of chronic periodontitis - A clinico-microbiological study.

Introduction: Chronic periodontitis (CP) is an infectious disease resulting in inflammation of the supporting tissues of the teeth with progressive attachment loss and bone loss. This study aimed to evaluate the effect of 980-nm diode laser, as an adjunct to scaling and root planing (SRP) in the management of CP.

Methodology: A total of 40 systemically healthy subjects diagnosed with CP were randomly assigned into two groups G1 (SRP and sham application of laser) and G2 (SRP and laser irradiation) with equal numbers in each.

Chair Side Application of NovaMin for the Treatment of Dentinal Hypersensitivity- A Novel Technique.

Objective: To evaluate the efficacy of calcium sodium phosphosilicate bioactive glass (NovaMin) as a chair side desensitizing agent.

Materials And Methods: The study was conducted on 60 subjects divided into 3 groups of 20 each as follows. Group I (NovaMin application without scaling and root planing), Group II (NovaMin application after scaling and root planing) and Group III (control group).

Health from the hive: propolis as an adjuvant in the treatment of chronic periodontitis - a clinicomicrobiologic study.

Objectives: This study was aimed at the clinical and microbiological evaluation of the efficacy of subgingivally delivered Indian propolis extract as an adjunct to scaling and root planing (SRP) in the treatment of periodontitis.

Materials And Methods: Twenty patients diagnosed with chronic periodontitis presenting a minimum of two pockets (probing depth ≥5 mm) were selected. Sites were assigned randomly into control sites (n=20) which received SRP alone or test sites (n=20) which received SRP and locally delivered propolis.

Correlation of the interleukin-29 levels in crevicular fluid and plasma with the genetic polymorphism in chronic and aggressive periodontitis patients.

Objective: To assess the effect of single nucleotide polymorphism (SNP) on the Interleukin (IL-29) quantity in gingival crevicular fluid (GCF) and plasma of chronic and aggressive periodontitis patients.

Design: Patients with periodontal health (n=30), chronic generalized periodontitis (n=30) and generalized aggressive periodontitis (n=30) were subjected to IL-29 quantity estimation in GCF and plasma using enzyme linked immunosorbent assay and was correlated with IL-29 SNP (rs30461) using polymerase chain reaction.

Results: IL-29 concentration in GCF and plasma was highest in aggressive periodontitis patients (114.

Expression profile of IL-35 mRNA in gingiva of chronic periodontitis and aggressive periodontitis patients: a semiquantitative RT-PCR study.

Background: Proinflammatory and anti-inflammatory cytokines play a key role in the pathogenesis of periodontal diseases. Secretion of bioactive IL-35 has been described by T regulatory cells (T(regs)) and is required for their maximal suppressive activity. T(regs) are involved in the modulation of local immune response in chronic periodontitis patients.

mRNA expression of MMP-28 (Epilysin) in gingival tissues of chronic and aggressive periodontitis patients: a reverse transcriptase PCR study.

Background And Objectives: Matrix metalloproteinases degrade extracellular membrane and also release bioactive fragments and growth factors, thus influencing fundamental biological and pathological processes. Epilysin (MMP-28) differs from most other MMPs as it is expressed in a number of normal tissues, suggestive of functions in tissue homeostasis. The aim of the present study was to quantitatively evaluate and compare the mRNA expression of epilysin (MMP-28) in gingival tissues of healthy patients and of patients affected by chronic or aggressive periodontitis.

Effect of non-surgical periodontal therapy on interleukin-29 levels in gingival crevicular fluid of chronic periodontitis and aggressive periodontitis patients.

Recently discovered interleukin 29 (IL-29) has antiviral properties and its production is induced by herpes viruses. This study was aimed at analyzing the effect of non-surgical periodontal treatment on IL-29 levels in gingival crevicular fluid (GCF) of chronic and aggressive periodontitis patients. A total of 60 participants were divided into healthy group (group 1; n=20), chronic periodontitis group (group 2; n=20), and aggressive periodontitis group (group 3; n=20).