Publications by authors named "Shivaprakash R"
Article Synopsis
- Fungal dysbiosis, particularly the presence of Candida, may play a role in the progression of inflammatory bowel disease, specifically ulcerative colitis (UC), although its effects and potential treatments like fluconazole are still being explored.
- In a study involving 242 patients with active UC, 28% were found to have Candida in their stool, with certain factors like Mayo score and steroid use linked to its presence.
- While fluconazole treatment showed some benefits in reducing symptoms and inflammatory markers compared to placebo, the overall clinical significance was not reached, suggesting more research is needed to fully understand the role of Candida and its treatment in UC.
A rapid, specific and sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the determination of penciclovir in human plasma. The method involved simple, one-step SPE procedure coupled with a C(18) , 75 × 4.mm, 3 µm column with a flow-rate of 0.
View Article and Find Full Text PDFA rapid, sensitive and rugged solid-phase extraction ultraperformance liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for determination of oseltamivir phosphate (OP) and oseltamivir carboxylate (OC) in human plasma. The procedure for sample preparation includes a simple SPE extraction procedure coupled with a Chromatopack C(18) column (50 × 3.0 mm, i.
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