Localization and expression analysis of sperm-specific glyceraldehyde 3-phosphate dehydrogenase in bull spermatozoa with contrasting sperm motility.

Background: Poor sperm motility leading to male infertility has become a profound crisis to be addressed in this contemporary era. In many cases, the origin of poor sperm motility remains unexplained. Few studies reported the indispensable role of sperm-specific glyceraldehyde 3-phosphate dehydrogenase (GAPDHS) in sperm motility, however, studies on GAPDHS are severely confined.

A Prospective Observational Study to Assess the Neutrophil-to-Lymphocyte Ratio (NLR) and C-reactive Protein-to-Albumin Ratio (CAR) in Predicting Morbidity and Mortality Among Patients Undergoing Emergency Abdominal Surgery.

Background Emergency abdominal surgeries pose significant challenges, especially in the Indian population, due to comorbidities, delayed presentations, and limited resources. Accurately predicting morbidity and mortality is crucial for timely interventions and improved patient care. The neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein-to-albumin ratio (CAR) have shown potential as prognostic markers, balancing inflammation and nutritional status.

Identification of potential differences in salivary proteomic profiles between estrus and diestrus stage of estrous cycle in dairy cows.

In the present study, a comparative global high-throughput proteomic analysis strategy was used to identify proteomic differences between estrus and diestrus stage of estrous cycle in dairy cows. Saliva was collected from cows during estrus and diestrus, and subjected to LC-MS/MS-based proteomic analysis. A total of 2842 proteins were detected in the saliva of cows, out of which, 2437 and 1428 non-redundant proteins were identified in estrous and diestrous saliva, respectively.

Sperm proteomic landscape is altered in breeding bulls with greater sperm DNA fragmentation index.

Although, it is well understood that sperm DNA damage is associated with infertility, the molecular details of how damaged sperm DNA affects fertility are not fully elucidated. Since sperm proteins play an important role in fertilization and post-fertilization events, the present study aimed to identify the sperm proteomic alterations in bulls with high sperm DNA Fragmentation Index (DFI%). Semen from Holstein-Friesian crossbred breeding bulls (n = 50) was subjected to Sperm Chromatin Structure Assay.

Prolonged follicular dominance is associated with dysregulated proteomic profile of the follicular fluid in Bos indicus cows.

Prolonged follicular dominance is one of the conditions associated with disconcerted follicular dynamics that result in substantial economic losses to the farmers through low reproductive efficiency in cattle. Hormonal aberrations associated with prolonged follicular dominance may affect the follicular microenvironment and composition of follicular fluid. The current study focused on proteome changes of follicular fluid in prolonged follicular dominance compared to physiological follicular dominance.

Identification of Novel Broad-Spectrum Leaf Rust Resistance Sources from Khapli Wheat Landraces.

Wheat leaf rust caused by Eriks is an important disease that causes yield losses of up to 40% in susceptible varieties. Tetraploid emmer wheat ( ssp. ) commonly called Khapli wheat in India, is known to have evolved from wild emmer ( var.

Recurrence of membranoproliferative glomerulonephritis post transplant - Is this mere recurrence of pattern or recurrence of disease?

Recurrence of membranoproliferative glomerulonephritis (MPGN) is seen in 1965% cases of postrenal transplant resulting in graft loss in up to 35-50% of cases. A 31-year-old female, after 1% years on maintenance hemodialysis, underwent ABO compatible deceased donor kidney transplantation with basiliximab induction. During the immediate posttransplant period, the patient had delayed graft function, but achieved nadir creatinine of 0.