Increased serum prolactin level may indicate more migraine attack frequency.

Objectives: Migraine is a common, multifactorial disorder. The exact pathomechanism of migraine remains unclear. Studies have revealed changes in serum prolactin (PRL) levels in relation to migraine, although the results have been inconsistent.

B vitamins and their combination could reduce migraine headaches: A randomized double-blind controlled trial.

The B vitamins can potentially help prevent migraine. This study was designed to examine the effects of supplementation with thiamine (B1), pyridoxine (B6), cobalamin (B12), folic acid (B9), and a combination of these vitamins on women with episodic migraine (EM). This study was a double-blind, placebo-controlled, randomized, clinical trial conducted on 120 women with EM.