Publications by authors named "Shiva Karimian"
Article Synopsis
- Monkeypox (Mpox) is an Orthopoxvirus causing skin blisters with a mortality rate of 0-10% and has seen an increase in cases since the end of global smallpox vaccinations.
- This review discusses updates on Mpox's transmission, symptoms, diagnosis, prevention, and treatment, highlighting the role of AI in predicting the disease.
- Key prevention strategies involve PCR testing for early detection, vaccination with JYNNEOS and ACAM2000, and minimizing contact with symptomatic individuals, similar to STI prevention practices.
In recent years, there has been a notable increase in the scientific community's interest in rational protein design. The prospect of designing an amino acid sequence that can reliably fold into a desired three-dimensional structure and exhibit the intended function is captivating. However, a major challenge in this endeavor lies in accurately predicting the resulting protein structure.
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- Diabetes is a growing global issue with long-term effects, and understanding the genetic factors is crucial for management.
- This study utilized bioinformatics tools to analyze differential gene expression between type 2 diabetes patients and normal individuals, identifying 21 significant hub genes and their interactions.
- Key findings highlight potential therapeutic targets like GLUL and SLC32A1, along with miRNAs hsa-miR-492 and hsa-miR-16-5p, which could play roles in the diagnosis and prognosis of the disease.