Computational modeling of tumor invasion from limited and diverse data in Glioblastoma.

For diseases with high morbidity rates such as Glioblastoma Multiforme, the prognostic and treatment planning pipeline requires a comprehensive analysis of imaging, clinical, and molecular data. Many mutations have been shown to correlate strongly with the median survival rate and response to therapy of patients. Studies have demonstrated that these mutations manifest as specific visual biomarkers in tumor imaging modalities such as MRI.

Cephalic and ocular manifestations of EBV-associated plasmablastic lymphoma: Clinical and radiological response to bortezomib, EPOCH, and intrathecal methotrexate.

Plasmablastic lymphoma (PBL) is a rare and aggressive type of lymphoma, particularly affecting HIV-positive and immunocompromised individuals, with a median diagnosis age of 49 years. Cases of this malignancy in HIV-negative individuals are less common and rarely involve the bone marrow. While traditional chemotherapy regimens such as cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) were previously utilized in the management of such malignancy, the National Comprehensive Cancer Network currently recommends more intensive approaches.

Giant phyllodes tumor of the breast: A case report.

Phyllodes tumors of the breast are rare fibroepithelial neoplasms that account for less than 1% of all breast tumors. They tend to affect middle-aged women, who present with a rapidly growing, palpable mass. Here we present a case of a 34-year-old female surrogate mother without any reported personal or family history of breast cancer who presented with a rapidly growing left breast mass, pathologically proven to be a phyllodes tumor.

Isolated torsion of fallopian tube with associated torsed paratubal cystadenofibroma: A case report.

Cystadenofibromas (CAF) and adenofibromas (AF) are rare benign gynecologic neoplasms of epithelial origin. They can be composed predominantly of solid fibrous tissue, adenofibromas, or contain cystic components, as seen in cystadenofibromas; which can be further classified by their epithelial cell type (serous, mucinous, etc.).

Enlarging premaxillary mass: A unique manifestation of extranodal diffuse B-cell lymphoma.

Lymphomas are the most common nonepithelial malignancy in the head and neck region. Among these, non-Hodgkin Lymphoma (NHL) is the most prevalent, and diffuse large B-cell lymphoma (DLBCL) is the most common histologic subtype. NHL is known for its propensity for extranodal involvement, which can affect any anatomical location.

A curious case of T2-FLAIR mismatch in H3K27M mutant glioma.

Diffuse midline gliomas are a rare relatively new classification of primary central nervous system tumors which include astrocytomas, oligodendrogliomas, and glioblastomas. The T2-FLAIR mismatch sign is regarded as a highly specific imaging feature of IDH-mutant, 1p/19q non-codeleted astrocytomas. The case presented herein demonstrates this sign, however, in a non-IDH mutated diffuse midline glioma with a H3K27M mutation, a World Health Organization Grade IV neoplasm.

Variations of magnetic resonance imaging findings in asymptomatic elbows.

Background: Magnetic resonance imaging (MRI) findings in asymptomatic patients have been described for hips, knees, ankles, shoulders, and intervertebral disks. No such description exists for the elbow.

Methods: MRI scans of 189 asymptomatic elbows divided into 3 groups by age (group 1, 20-39 years; group 2, 40-59 years; and group 3, ≥60 years) were evaluated for abnormalities within 13 anatomic structures using a novel classification system.

Invasive Colloid Carcinoma and the role of Ki-67 and HER2 - Two case reports.

Mucinous carcinoma (also termed colloid carcinoma) of the breast accounts for 1%-6% of all breast cancer and is considered to have a good relative prognosis. The most common mammographic appearance of pure mucinous carcinoma is a high-density mass with circumscribed margins and on sonographic examination an isoechoic round mass with circumscribed margins. We report 2 cases of invasive mucinous carcinoma, in which one patient showed an intermediate recurrence risk based on Ki-67 and human epidermal growth factor receptor 2 negativity, while the other showed a low Ki-67 recurrence risk and human epidermal growth factor receptor 2 positive.

Perforation of the IVC: rule rather than exception after longer indwelling times for the Günther Tulip and Celect retrievable filters.

Purpose: This study was designed to assess the incidence, magnitude, and impact upon retrievability of vena caval perforation by Günther Tulip and Celect conical inferior vena cava (IVC) filters on computed tomographic (CT) imaging.

Methods: Günther Tulip and Celect IVC filters placed between July 2007 and May 2009 were identified from medical records. Of 272 IVC filters placed, 50 (23 Günther Tulip, 46%; 27 Celect, 54%) were retrospectively assessed on follow-up abdominal CT scans performed for reasons unrelated to the filter.