Publications by authors named "Shitong Liu"

Background: This study explores the potential of the deep learning-based convolutional neural network (CNN) to automatically recognize MMD using MRA images from atherosclerotic disease (ASD) and normal control (NC).

Methods: In this retrospective study in China, 600 participants (200 MMD, 200 ASD and 200 NC) were collected from one institution as an internal dataset for training and 60 from another institution were collected as external testing set for validation. All participants were divided into training (N = 450) and validation sets (N = 90), internal testing set (N = 60), and external testing set (N = 60).

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  • - This study explores the link between multiple sclerosis (MS) and the outcomes of COVID-19, using genetic analysis to determine if factors like the SNP rs10191329 impact MS patients' susceptibility to severe COVID-19 cases.
  • - Researchers used genetic data to conduct a Mendelian randomization analysis, revealing that while MS might increase COVID-19 risk, carriers of the rs10191329 SNP were less likely to suffer severe COVID-19 symptoms.
  • - The study found no significant impact of interferon beta (IFNβ) treatment on COVID-19 outcomes in MS patients, suggesting that IFNβ might provide protective effects against SARS-CoV-2, highlighting the need for further research on targeted treatments during the pandemic
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Chalcopyrite has evolved into a crucial source of copper pollution, and xanthates inevitably coexisted with chalcopyrite in mine environments. However, the effect of xanthate on chalcopyrite bio-dissolution has not been illustrated yet. To fill this knowledge gap, the effect of potassium amyl xanthate (KAX) on copper release from chalcopyrite mediated by Acidithiobacillus ferrooxidans was investigated.

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Upgrading processes to reduce biodegradable organic substance addition is crucial for treating landfill leachate with high pollutant concentrations, aiding carbon emission reduction. Aggregate size in activated sludge processes impacts pollutant removal and sludge/water separation. This study investigated microbial community succession and driving mechanisms in different floc-size aggregates during nitrogen removal progress upgrade from conventional to partial nitrification-denitrification in a full-scale landfill leachate treatment plant (LLTP) using 16S rRNA gene sequencing.

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Red mud (RM) is a typical bulk solid waste with Fe/Al/Si/Ca-rich characteristics that has been used to prepare various heterogeneous catalysts such as iron-based catalysts and supported catalysts. Prussian blue analogues (PBA) is a low-cost, environmentally friendly, and active site rich iron-based metal organic framework, but its catalytic properties are adversely affected by their easy aggregation. In this study, nickel-doped RM-based PBA (RM-Ni PBA) was synthesized by acid dissolution-coprecipitation method for the degradation of ciprofloxacin (CIP).

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Background: To explore the risk factors for preoperative massive cerebral infarction (MCI) in pediatric patients with moyamoya disease (MMD).

Methods: Pediatric patients with MMD treated between 2017 and 2022 were enrolled. Logistic regression analysis was performed to identify risk factors for MCI among the patients, and a nomogram was constructed to identify potential predictors of MCI.

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This study proposes a novel method by forming biogenic K-jarosite coatings on pyrite surfaces driven by Acidithiobacillus ferrooxidans (A. ferrooxidans) to reduce heavy metal release and prevent acid mine drainage (AMD) production. Different thicknesses of K-jarosite coatings (0.

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  • Intracranial vessel wall enhancement (VWE) on high-resolution MRI is linked to worse outcomes in patients with moyamoya disease (MMD), prompting a study to identify risk factors for VWE.
  • *The study involved 283 MMD patients, identifying 84 with VWE and finding risk factors such as the RNF213 gene variant, hyperhomocysteinaemia, and smoking history leading to higher incidences of cerebrovascular events.
  • *Ultimately, the RNF213 p.R4810K variant is a significant predictor of VWE and poor prognosis, highlighting the importance of these risk factors in clinical assessments for MMD.*
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The massive accumulation of red mud (RM) and the abuse of antibiotics pose a threat to environment safety and human health. In this study, we synthesized RM-based Prussian blue (RM-PB) by acid solution-coprecipitation method to activate HO to degrade norfloxacin, which reached about 90% degradation efficiency at pH 5 within 60 min and maintained excellent catalytic performance over a wide pH range (3-11). Due to better dispersion and unique pore properties, RM-PB exposed more active sites, thus the RM-PB/HO system produced more reactive oxygen species.

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Today, with the globalization of the food trade progressing, food safety continues to warrant widespread attention. Foodborne diseases caused by contaminated food, including foodborne pathogens, seriously threaten public health and the economy. This has led to the development of more sensitive and accurate methods for detecting pathogenic bacteria.

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  • The study focuses on how the characteristics of the extracranial internal carotid artery (EICA) in patients with Moyamoya disease (MMD) can affect the outcomes of revascularization treatments, which is not well understood.
  • Using high-resolution MRI techniques, researchers examined the EICA features, including stenosis, wall thickening, and plaques, in 288 adult MMD patients to see their impact on stroke outcomes.
  • They employed statistical methods like Cox proportional hazards models and Kaplan-Meier curves to analyze data over an average follow-up of 8 months, identifying the predictive quality of EICA features in combination with intracranial artery conditions for stroke risk.
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Studies have shown that exposure to fine particulate matter (PM2.5) affects various cells, systems, and organs in vivo and in vitro. PM2.

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Objectives: To evaluate the diagnostic performance of high-resolution magnetic resonance-vessel wall imaging (HRMR-VWI) in differentiating moyamoya disease (MMD) from atherosclerosis-associated moyamoya vasculopathy (AS-MMV) and investigate an accurate approach for the differential diagnosis.

Methods: Adult patients who were diagnosed as MMD or AS-MMV and underwent HRMR-VWI were retrospectively included. The three vessel wall features (outer diameter (OD), remodeling index (RI), and pattern of vessel wall thickening) of middle cerebral artery (MCA) in identifying MMD from AS-MMV were assessed and compared.

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With the development of new technologies for rapid and high-throughput bacterial detection, ATP-based bioluminescence technology is making progress. Because live bacteria contain ATP, the number of bacteria is correlated with the level of ATP under certain conditions, so that the method of luciferase catalyzing the fluorescence reaction of luciferin with ATP is widely used for the detection of bacteria. This method is easy to operate, has a short detection cycle, does not require much human resources, and is suitable for long-term continuous monitoring.

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  • The study investigates the long-term risk factors for stroke in 160 conservatively treated patients with moyamoya disease (MMD), specifically evaluating clinical and imaging features.
  • It recorded a median follow-up of 47 months, finding that 11.25% of patients experienced stroke events, primarily ischemic strokes.
  • Key independent risk factors identified include a modified Rankin score of 3 or higher, decreased cerebral blood volume, and concentric enhancement of the arterial wall in imaging assessments.
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  • The study compared long-term outcomes and surgical benefits between two types of moyamoya disease: classic moyamoya disease (MMD) and atherosclerosis-associated moyamoya vasculopathy (AS-MMV) using high-resolution MRI.
  • Out of 1173 patients, MMD patients showed a higher incidence of cerebrovascular events compared to AS-MMV patients during an average follow-up period of about 46 months.
  • Both MMD and AS-MMV patients exhibited lower event rates when treated with encephaloduroarteriosynangiosis (EDAS), indicating that this surgical option is beneficial for both conditions.
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Objectives: This study aimed to determine the association between vessel wall enhancement and progression of arterial stenosis and clinical outcomes in patients with moyamoya (MMD) using high-resolution magnetic resonance (HRMR) vessel wall imaging.

Methods: Consecutive participants diagnosed with MMD were prospectively recruited and underwent HRMR at baseline and during follow-up, which had an interval period of ≥ 6 months and were clinically followed up for ≤ 24 months to record the occurrence of ischemic stroke. The relationship between vessel wall enhancement and arterial stenosis progression and stroke occurrence was evaluated.

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Background And Purpose: 3D pseudo-continuous arterial spin labeling (3D pCASL) is commonly used to measure arterial cerebral blood flow (CBF). The aim of this study was to assess the clinical feasibility and accuracy of 3D pCASL in comparison with dynamic susceptibility contrast (DSC) perfusion imaging in moyamoya disease (MMD).

Materials And Methods: A total of 174 MMD patients underwent 3D pCASL and DSC-MRI for evaluating cerebral blood perfusion.

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Background And Purpose: This study aimed to investigate the arterial disease risk factors for the progression of intraplaque hemorrhage (IPH) in patients with carotid atherosclerosis using serial high-resolution magnetic resonance (MR) imaging.

Methods: Consecutive symptomatic patients who had MRI evidence of intraplaque hemorrhage present in the ipsilateral carotid artery with respect to the side of the brain affected by stroke or TIA were recruited in the study. All the patients underwent follow-up MR imaging at least 6 months after baseline.

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Background: This study aimed to compare the characteristics of carotid plaques between patients with transient ischemic attack (TIA) and ischemic stroke using magnetic resonance (MR) imaging.

Methods: Patients with a recent ischemic stroke or TIA who exhibited atherosclerotic plaques of carotid arteries in the symptomatic sides determined by MR vessel wall imaging were recruited. The plaque morphology and compositions including intraplaque hemorrhage (IPH), lipid-rich necrotic-core (LRNC) and calcification were compared between TIA and stroke patients.

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The food-derived peptides hydrolyzed from native food protein matrix exhibited various bioactivities and multimeric structures, which make them the promising well-defined nanoplatforms candidates to co-deliver themselves with other bioactive compounds. In this study, zein-egg white derived peptides-chitosan (Z-EWDP-CS) ternary nanoparticles (NPs) were successfully fabricated by the spontaneous assembly to enhance the stability and bioactivity of curcumin (Cur). The novel ternary NPs exhibited a typical nano-spherical structure (138.

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Background And Purpose: This study aimed to investigate the enhancement characteristics of vessel wall in patients with moyamoya disease (MMD) using 3D high-resolution magnetic resonance (MR) imaging and their relationship with initial and recurrent intracranial hemorrhage.

Methods: Consecutive patients with MMD were retrospectively analyzed and classified as intracranial hemorrhagic and non-hemorrhagic groups according to the CT or MR images. The clinical features and vessel wall characteristics were compared between the two groups.

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Chalcopyrite is a crucial contributor causing acid mine drainage (AMD). Silver and pyrite are commonly co-existed with chalcopyrite, and can significantly affect the copper release from chalcopyrite bio-dissolution process. However, the combined effect of them on chalcopyrite bio-dissolution has not been illustrated up to now.

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