Vestn Oftalmol
December 2024
Unlabelled: The scientific and practical interest in studying the biomechanical characteristics of the lens capsule, on the one hand, is associated with its anatomical significance in modern microinvasive phaco surgery, and on the other hand, with investigation of the mechanisms of lens curvature changes during accommodation. Selective study of the biomechanical properties of the lens capsule aims to identify characteristics of various regions and surfaces of the capsule.
Purpose: This study is a comparative analysis of age-related changes in the biomechanical properties of the anterior (AC) and posterior (PC) lens capsules in humans.
Aseptic seedlings of different ages derived from surface-sterilized mature seeds were applied as an explant source. Various explants such as 7- and 21-day-old hypocotyl fragments, 42-day-old nodal stem segments, and transverse nodal segments of stem, as well as leaf petioles, were cultured on the agar-solidified Murashige and Skoog (MS) basal medium supplemented with 0.1 mg/L IAA, 5 mg/L AgNO and different types and concentrations of cytokinin (1 mg/L zeatin, 0.
View Article and Find Full Text PDFOptical coherence tomography of the anterior segment of the eye (AS-OCT) is a non-invasive method based on the principles of optical reflectometry (measurement of the degree of backscattering of light passing through transparent or translucent media). Limitations of the first devices of this type were associated with insufficient image quality of the details of the anterior chamber angle and the posterior parts of the lens, primarily due to the "working" level of the scanning wavelength (within 800 μm). Fundamentally new possibilities in the structural and functional assessment of the anterior segment of the eye are associated with the introduction into clinical practice of swept-source AS-OCT device - the CASIA2 anterior optical coherence tomograph (Tomey Corporation, Japan).
View Article and Find Full Text PDFThe article reviews the findings on the anatomy, morphological and biomechanical features of the accommodation apparatus. Modern methods of imaging and biometry confirm the validity of the Helmholtz lenticular theory of accommodation, according to which its mechanism involves three main components: the ciliary body, the zonular fibres and the lens capsule, the lens itself. Based on this, there is certain interest in studying the degree of participation of each of these components in the development of age-related changes in accommodation (presbyopia).
View Article and Find Full Text PDFUnlabelled: Studies devoted to the assessment of lens capsule biomechanics can be divided into fundamental and applied. The former are oriented towards analysis of various indicators characterizing elasticity of the capsule as a basal membrane that maintains and changes the shape of the lens, and the latter deal with widespread introduction of modern microinvasive methods of phaco surgery into clinical practice.
Purpose: To assess age-related changes in lens capsule biomechanics based on atomic force microscopy (AFM).
The application of atomic force microscopy (AFM) in ophthalmology is considered with respect of the classical anatomical division of the eye into anterior and posterior segments. The review presents the findings of published research studies that involved AFM as a method for assessing anatomical and functional condition of the structures of anterior eye segment. One significant line of research is related to the use of AFM technologies for evaluation of morphological and biomechanical characteristics of various parts of the eye lens.
View Article and Find Full Text PDFThe authors offer a visual method for assessing the intravascular platelet activation, based on examination under phase-contrast microscope of changes in the shape and relative number of blood platelets in aggregations. Results of examinations of patients with different thrombotic diseases are presented.
View Article and Find Full Text PDFDirect measurement of the force of clot contraction from the plasma in normal subjects and standardization of plasma platelet count, carried out with a retractograph, a newly designed apparatus, have helped assess the platelet retractile activity. Linear relationship between platelet count in the clot from the plasma and the force of the clot contraction, detected in normal subjects, allows one to do without standardization of the platelet count to a preset level when measuring the blood platelet retractile activity in patients.
View Article and Find Full Text PDFProbl Gematol Pereliv Krovi
March 1978
The literature data on the condition of the platelet part of the homeostasis in patients with acute leukemia are summarized. The importance of functional changes in blood plates in the development of hemorrhagic complications is demonstrated. In acute leukemia, the development of various platelet syndromes such as thrombasthenia, thrombocytopathy, including a deficiency of the pool of storage of athrombia is possible.
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