Synopsis of recent research by authors named "Shisi Wang"
- Shisi Wang's recent research primarily focuses on the interplay between vascular and neurodegenerative diseases, particularly highlighting the pathological mechanisms underlying conditions such as cerebral small vessel disease (CSVD) and cerebral amyloid angiopathy (CAA) along with their neuroinflammatory consequences.
- A significant finding reveals that intra-cisterna-magna bevacizumab injection induces direct damage to cerebral small blood vessels, resulting in neurological impairments and characteristic features of CSVD, while chronic stress was shown to exacerbate CAA progression by promoting harmful protein depositions.
- Additionally, Wang's studies explore potential therapeutic approaches, including the use of bone marrow mesenchymal stem cells to mitigate post-stroke complications and the neuroprotective effects of melatonin on brain endothelial cells during ischemic events, demonstrating promising avenues for treatment in cerebrovascular disorders.
