Understanding admixture fractions: theory and estimation of gene-flow.

Estimation of admixture proportions has become one of the most commonly used computational tools in population genomics. However, there is remarkably little population genetic theory on statistical properties of these variables. We develop theoretical results that can accurately predict means and variances of admixture proportions within a population using models with recombination and genetic drift.

[Biomechanics of diabetic vitreopapillary traction syndrome].

Diabetic vitreopapillary traction syndrome (VPT) is a variant of diabetic retinopathy (DR) that can lead to vision loss in advanced stages. This review reports on the biomechanics of the vitreous in the pathogenesis of proliferative DR, in particular diabetic VPT. The article analyzes and summarizes literature data, presents the views of different authors on this problem, and provides the results of Russian and foreign scientific research on this pathology.

Dataset on elemental composition of soils and plants under long-term application of mineral and organic fertilizers on gray forest soils in Vladimir region, Russia.

Long-term application of organic and mineral fertilizers can lead to changes in the elemental composition of agroecosystem components. Both the levels of nutrients and potentially toxic elements can change, as can the potential for these elements to be available to plants through changes in soil properties. Soil and plant samples of two species (pea L.

[Episcleral circular buckling in surgical treatment of recurrent rhegmatogenous retinal detachment after vitrectomy].

Unlabelled: Despite the improvement of the surgical technique of vitreoretinal interventions, the number of recurrences of rhegmatogenous retinal detachment (RRD) remains quite high.

Purpose: Evaluation of the effectiveness of episcleral circular buckling (ECB) in the treatment of recurrent RRD after vitrectomy due to progression of proliferative vitreoretinopathy (PVR).

Material And Methods: The study analyzed the results of surgical treatment of 21 patients (21 eyes) with recurrent RRD after primary vitrectomy.

Circulating Marangoni flows within droplets in smectic films.

We present a theoretical study and numerical simulation of Marangoni convection within ellipsoidal isotropic droplets embedded in free-standing smectic films (FSSFs). The thermocapillary flows are analyzed for both isotropic droplets spontaneously formed in FSSF overheated above the bulk smectic-isotropic transition and oil lenses deposited on the surface of the smectic film. The realistic model for which the upper drop interface is free from the smectic layers, while at the lower drop surface the smectic layering persists is considered in detail.

Estimating the timing of multiple admixture events using 3-locus linkage disequilibrium.

Estimating admixture histories is crucial for understanding the genetic diversity we see in present-day populations. Allele frequency or phylogeny-based methods are excellent for inferring the existence of admixture or its proportions. However, to estimate admixture times, spatial information from admixed chromosomes of local ancestry or the decay of admixture linkage disequilibrium (ALD) is used.

[Modern aspects of the treatment of submacular hemorrhages secondary to macular degeneration].

Age-related macular degeneration complicated by submacular hemorrhage if not treated timely leads to permanent loss of central vision. The basis of effective therapy is its early start, dislocation of blood from central parts of the retina and blockage of neovascularization. This review examines the current methods of treatment of submacular hemorrhages, anatomical and functional outcomes, risks of postoperative complications, as well as trends in the use of combined methods of surgical intervention.

[Vitreopapillary traction syndrome in patients with proliferative diabetic retinopathy].

Purpose: To draw attention to characteristic features of the clinical manifestations of vitreopapillary traction syndrome (VPTS) in patients with proliferative diabetic retinopathy (PDR), to determine the role of the biomechanical factor in pathophysiology of this syndrome, and to evaluate the results of surgical treatment.

Material And Methods: The features of clinical manifestations of VPTS of 50 patients with PDR who were treated at the ophthalmology center of the National Medical and Surgical Center named after N.I.

Evaluation of redox potentials of cathode materials of alkali-ion batteries using extended DFT+U+U method: The role of interactions between the electrons with opposite spins.

Limitations of the DFT+U approach (e.g., in Dudarev's formulation) applied for accurate evaluation of redox potentials of cathode materials of alkali-ion batteries with U parameters calculated via the linear response (LR) method are discussed.

[Protocol of intravitreal drug delivery. Consensus of the Expert Counsil of Retina and Optic Nerve Diseases of the All-Russian Public Organasation «Association of Ophthalmologists»].

Intravitreal drug administration is a procedure that has become widespread in modern ophthalmology. However, there is no global consensus on certain aspects of this manipulation, and practitioners feel the need for guidelines. In the Russian Federation, until now, such a document was not available.

[Effectiveness of multistage surgical treatment of advanced proliferative diabetic retinopathy complicated with primary cataract].

Unlabelled: Vitreoretinal surgery (VRS) is the «gold standard» for surgical treatment of patients with proliferative diabetic retinopathy (PDR). However, the timing for the removal of primary cataract in this category of patients remains uncertain.

Purpose: To evaluate the effectiveness of multistage surgical treatment of patients with advanced PDR complicated with primary cataract.

[Changes in perfusional and morphological parameters of the macular area after silicone oil tamponade of the vitreous cavity].

Purpose: To compare the changes of the macular morphological and functional parameters in the postoperative period in patients with silicone oil tamponade after successful surgery of the macula-on rhegmatogenous retinal detachment (RRD).

Material And Methods: The study included 20 eyes operated on for macula-on RRD, which made up the first group, and the control group (20 eyes) for comparison. All patients of the study group underwent vitrectomy using silicone oil tamponade.

[Influence of treatment adherence on the progression of primary open-angle glaucoma in clinical setting].

Unlabelled: According to various studies, treatment adherence of patients with primary open-angle glaucoma ranges from 5% to 80% and significantly influences the effectiveness of the therapy. Some authors report higher levels of adherence in patients receiving preservative-free medications.

Purpose: To study the influence of treatment adherence in patients receiving preservative-free and preserved medications on the progression of primary open-angle glaucoma (POAG).

DFT+U in Dudarev's formulation with corrected interactions between the electrons with opposite spins: The form of Hamiltonian, calculation of forces, and bandgap adjustments.

Hubbard corrected density functional theory (DFT) methods, such as the DFT+U approach in Dudarev's approximation, are widely used for the description of energetics and electronic structure of strongly correlated materials, providing higher level of accuracy than local DFT calculations (e.g., local density approximation or generalized gradient approximation).

Theoretical Analysis of Materials, used in Energy Storage Applications: the Quest for Robust and Accurate Computational Methodologies.

Study of materials, used as constituents for energy storage devices (e. g. Li- or Na-ion batteries) has been greatly enhanced by the first principles theoretical modeling.

Evolution as a search for organizational equilibrium.

Evolution of living systems is a succession of historical changes in their equilibrium states. In the individual life cycle, every such state is realized as an equilibrium of developmental system, i.e.

[Cephalometry efficacy in orthodontic treatment planning: correlations of cephalometric values and their changes in the course of treatment].

The aim of the study was to assess the efficacy of cephalometry in planning of orthodontic patients with teeth crowding (TC) and Angle Class I molar relationship (MR). Cephalometric values of 70 patients with TC and class I MR were analyzed before and after orthodontic treatment. Cephalometric study of correlations proved to be more relevant than comparing with mean values.

Optoacoustic determination of analytical parameters and physicochemical constants in highly concentrated solutions of chromophores.

Determination of chromophores of various classes-rosaniline (fuchsine), cyanidin-3-O-glucoside, tris(1,10-phenanthroline) iron(II), and phenol red - in their concentrated solutions near their solubility limits is performed with the optoacoustic technique for optically dense solutions; light-absorption coefficients of samples range from 0.5 to 500cm. The assessment of these substances in organo-aqueous and organic solvents is possible up to ca.

[Efficiency of cephalometry in orthodontic treatment planning: cephalometric parameters and their age-related changes].

The aim of the study was to evaluate the efficiency of cephalometry in orthodontic treatment planning in patients with teeth crowding and Angle Class I molars relation. Cephalometric parameters were analyzed in 70 patients that completed orthodontic treatment in 'Orthodont' dental clinic (Samara). Cephalometric X-rays were taken at baseline examination and after treatment.

Challenges in computational evaluation of redox and magnetic properties of Fe-based sulfate cathode materials of Li- and Na-ion batteries.

Several Fe-based sulfates have been proposed recently as cathode materials characterized by a high average operating voltage (i.e. LiFe(SO) and NaFe(SO)) or low fabrication temperature (e.

[Clinical and epidemiological characteristics of hemorrhagic fever with renal syndrome in the North-West region of Russia].

The data of the literature and our own research of clinical and epidemiological features of hantavirus infection the North-West region of Russia, showing the loss of endemicity of hemorrhagic fever with renal syndrome. It is noted mostly airborne infection in young and middle-aged men, year-round nature of the disease with seasonal peaks. The clinical picture is moderately prevalent the disease with no or minimal systemic manifestation of hemorrhagic syndrome, often marked by thrombocytopenia, moderate dysfunction and kidney damage in half the time without reducing urine output.

Direct solubility determination in optically dense solutions of highly soluble chromophores by the optoacoustic technique: Acidity dependence for Phenol Red.

The optoacoustic (OA) technique capable for light-absorption measurements in highly concentrated solutions is applied for direct solubility assessment in highly absorbing saturated solutions without any dilution or sample preparation. Maximum solubility of Phenol Red in aqueous solutions at pH>11 is found to be 1.3±0.

[Organisation of medical care to military personnel with viral hepatitis. A during the local armed conflicts].

Organisation of medical care to military personnel with viral hepatitis A during the local armed conflicts. The article provides an analysis of medical care organisation system to patients with viral hepatitis A during conducting counterterror operations on the North Caucasus (1994-1996 and 1999-2002). The authors provided information on the main problems of medical support in modern local armed conflicts and shortcomings of organization of medical care to patients with viral hepatitis A in the following conditions: multistage, discrepancy between calculation of forces and facilities and character of military conditions, shortcoming of staff structure of medicalfacilities, inappropriate level ofproficiency ofphysicians of infectious profile and absence of regulations, concerning the use for equipment of infectious hospitals.

[Stability of orthodontic correction: preconditions of relapses caused by occlusal forces].

The aim of the study was to determine the prognostic criteria of orthodontic treatment success in a group of patients with crowded teeth position and a neutral occlusion. The study included 150 patients (123 female and 27 male) with the average follow-up of 10.02±2.